48,830
edits
Difference between revisions of "Renal mucinous tubular and spindle cell carcinoma"
Jump to navigation
Jump to search
Renal mucinous tubular and spindle cell carcinoma (view source)
Revision as of 15:34, 28 February 2014
, 15:34, 28 February 2014split out
(+cat.) |
(split out) |
||
| Line 1: | Line 1: | ||
'''Renal mucinous tubular and spindle cell carcinoma''', abbreviated '''RMTSCC''', is a rare malignant epithelial neoplasm of the [[kidney]]. | |||
It is also known as '''renal mucinous tubular spindle cell carcinoma''' and | |||
'''mucinous tubular and spindle cell carcinoma of the kidney'''.<ref name=pmid16258504>{{Cite journal | last1 = Brandal | first1 = P. | last2 = Lie | first2 = AK. | last3 = Bassarova | first3 = A. | last4 = Svindland | first4 = A. | last5 = Risberg | first5 = B. | last6 = Danielsen | first6 = H. | last7 = Heim | first7 = S. | title = Genomic aberrations in mucinous tubular and spindle cell renal cell carcinomas. | journal = Mod Pathol | volume = 19 | issue = 2 | pages = 186-94 | month = Feb | year = 2006 | doi = 10.1038/modpathol.3800499 | PMID = 16258504 }}</ref> | |||
==General== | |||
*Rare.<ref name=pmid19494850>{{Cite journal | last1 = Srigley | first1 = JR. | last2 = Delahunt | first2 = B. | title = Uncommon and recently described renal carcinomas. | journal = Mod Pathol | volume = 22 Suppl 2 | issue = | pages = S2-S23 | month = Jun | year = 2009 | doi = 10.1038/modpathol.2009.70 | PMID = 19494850 }}</ref> | |||
*Accepted by WHO in 2004 as a separate entity.<ref name=pmid19805959>{{cite journal |author=Geramizadeh B, Salehipour M, Moradi A |title=Mucinous tubular and spindle cell carcinoma of kidney: a rare case report and review of the literature |journal=Indian J Pathol Microbiol |volume=52 |issue=4 |pages=514–6 |year=2009 |pmid=19805959 |doi=10.4103/0377-4929.56144 |url=}}</ref> | |||
*Relatively good prognosis. | |||
==Microscopic== | |||
Features:<ref name=pmid19066686>{{cite journal |author=Trabelsi A, Stita W, Yacoubi MT, Rammeh S, Hmissa S, Korbi S |title=Renal mucinous tubular and spindle cell carcinoma |journal=Can Urol Assoc J |volume=2 |issue=6 |pages=635–6 |year=2008 |month=December |pmid=19066686 |pmc=2593603 |doi= |url=}}</ref> | |||
*Mucin (foamy macrophages) - may be scant. | |||
*Spindle cells - '''key feature'''. | |||
DDx: | |||
*Sarcomatoid [[papillary renal cell carcinoma]].<ref name=pmid18941398>{{cite journal |author=Dhillon J, Amin MB, Selbs E, Turi GK, Paner GP, Reuter VE |title=Mucinous tubular and spindle cell carcinoma of the kidney with sarcomatoid change |journal=Am. J. Surg. Pathol. |volume=33 |issue=1 |pages=44–9 |year=2009 |month=January |pmid=18941398 |doi=10.1097/PAS.0b013e3181829ed5 |url=}}</ref> | |||
*[[Renal mucinous tubular and spindle cell carcinoma]]. | |||
===Images=== | |||
www: | |||
*[http://moon.ouhsc.edu/kfung/jty1/OPAQ/PathQuiz-Answer/K1A001-PQ01-Ans.htm RMTSCC (ouhsc.edu)]. | |||
*[http://www.cttr.org/large/02146b.jpg RMTSCC (cttr.org)].<ref>URL: [http://www.cttr.org/cms/?p=1406 http://www.cttr.org/cms/?p=1406]. Accessed on: 28 February 2014.</ref> | |||
==IHC== | |||
Features:<ref name=pmid16231179>{{cite journal |author=Ferlicot S, Allory Y, Compérat E, ''et al.'' |title=Mucinous tubular and spindle cell carcinoma: a report of 15 cases and a review of the literature |journal=Virchows Arch. |volume=447 |issue=6 |pages=978–83 |year=2005 |month=December |pmid=16231179 |doi=10.1007/s00428-005-0036-x |url=}}</ref> | |||
*CD10 -ve. | |||
*AE1/AE3 +ve. | |||
*AMACR +ve. | |||
*CK7 +ve. | |||
==See also== | |||
*[[Renal tumours]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Renal tumours]] | |||