Difference between revisions of "Squamous cell carcinoma of the head and neck"

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*[http://commons.wikimedia.org/wiki/File:Oral_cancer_(1)_squamous_cell_carcinoma_histopathology.jpg?uselang=de Invasive oral SCC (WC)].
*[http://commons.wikimedia.org/wiki/File:Oral_cancer_(1)_squamous_cell_carcinoma_histopathology.jpg?uselang=de Invasive oral SCC (WC)].


==Overview of subtypes==
===Overview of subtypes===
There are several subtypes:<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970297-2 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970297-2]. Accessed on: March 9, 2010.</ref>
There are several subtypes:<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970297-2 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970297-2]. Accessed on: March 9, 2010.</ref>
*Basaloid - poor prognosis, usu. diagnosed by recognition of typical SCC.
*Basaloid - poor prognosis, usu. diagnosed by recognition of typical SCC.
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*Spindle cell, a common spindle cell lesion of the H&N.
*Spindle cell, a common spindle cell lesion of the H&N.


===Verrucous squamous cell carcinoma===
====Verrucous squamous cell carcinoma====
Features:
Features:
*Exophytic growth.
*Exophytic growth.
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DDx: papilloma.
DDx: papilloma.


===Spindle cell squamous carcinoma===
====Spindle cell squamous carcinoma====
*Key to diagnosis is finding a component of conventional squamous cell carcinoma.
*Key to diagnosis is finding a component of conventional squamous cell carcinoma.


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*Mesenchymal neoplasm.
*Mesenchymal neoplasm.


===Basaloid squamous cell carcinoma===
====Basaloid squamous cell carcinoma====
*May mimic ''[[adenoid cystic carcinoma]]''.
*May mimic ''[[adenoid cystic carcinoma]]''.
*Classically base of tongue.<ref>URL: [http://www.biomedcentral.com/1471-2407/6/146 http://www.biomedcentral.com/1471-2407/6/146]. Accessed on: March 9, 2010.</ref>
*Classically base of tongue.<ref>URL: [http://www.biomedcentral.com/1471-2407/6/146 http://www.biomedcentral.com/1471-2407/6/146]. Accessed on: March 9, 2010.</ref>
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*Neuroendocrine tumour.
*Neuroendocrine tumour.


===Lymphoepithelial (squamous cell) carcinoma===
====Lymphoepithelial (squamous cell) carcinoma====
See ''[[nasopharyngeal carcinoma]]''.
See ''[[nasopharyngeal carcinoma]]''.


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