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Nodular hyperplasia of the prostate gland (view source)
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'''Nodular hyperplasia of the prostate gland''', also '''benign prostatic hyperplasia''' (abbreviated '''BPH'''), is a common benign pathology of the [[prostate gland]]. | |||
It is also known as '''prostatic nodular hyperplasia'''. Occasionally, it is referred to as | |||
'''benign prostatic hypertrophy'''; this is a misnomer. This pathology is ''not'' a hypertrophy. | |||
==General== | |||
*Very common. | |||
*Incidence increases with age. | |||
Clinical - mnemonic ''I WISH 2p'':<ref>{{Ref TN2006| U5}}</ref> | |||
*Intermittency. | |||
*Weak stream. | |||
*Incomplete emptying. | |||
*Straining. | |||
*Hesitancy. | |||
*Post-void dribbling. | |||
*Prolonged voiding. | |||
Treatment: | |||
*Medications. | |||
*Transurethral resection of the prostate (TURP). | |||
==Gross== | |||
*Enlargement of the prostate. | |||
*Nodularity of the prostate. | |||
==Microscopic== | |||
Features: | |||
*Stromal and/or glandular hyperplasia. | |||
Note: | |||
*Should '''not''' be diagnosed on core biopsy! | |||
DDx: | |||
*[[Urothelial carcinoma]] - significant nuclear atypia. | |||
===Images=== | |||
<gallery> | |||
Image:Nodular_hyperplasia_of_the_prostate.jpg | Prostatic nodular hyperplasia. (WC/Nephron) | |||
</gallery> | |||
==Sign out== | |||
===Urothelium present=== | |||
<pre> | |||
PROSTATE TISSUE, TRANSURETHRAL RESECTION OF THE PROSTATE (TURP): | |||
- BENIGN PROSTATIC TISSUE WITH GLANDULAR AND STROMAL PROLIFERATION. | |||
- UROTHELIAL MUCOSA WITH A MILD LYMPHOCYTIC INFILTRATE. | |||
- NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
<pre> | |||
PROSTATE TISSUE, TRANSURETHRAL RESECTION OF THE PROSTATE (TURP) AND URINARY BLADDER NECK: | |||
- BENIGN PROSTATIC TISSUE WITH GLANDULAR AND STROMAL PROLIFERATION. | |||
- UROTHELIUM WITH THE CHANGES OF CYSTITIS CYSTICA ET GLANDULARIS. | |||
- NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
<pre> | |||
PROSTATE TISSUE, TRANSURETHRAL RESECTION OF THE PROSTATE (TURP) AND URINARY BLADDER NECK: | |||
- BENIGN PROSTATIC TISSUE WITH GLANDULAR AND STROMAL PROLIFERATION, AND FOCAL | |||
ACUTE AND CHRONIC INFLAMMATION. | |||
- UROTHELIUM WITH THE CHANGES OF CYSTITIS CYSTICA ET GLANDULARIS. | |||
- NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
===No urothelium present=== | |||
<pre> | |||
PROSTATE GLAND, TRANSURETHRAL RESECTION OF THE PROSTATE (TURP): | |||
- BENIGN PROSTATIC TISSUE WITH GLANDULAR AND STROMAL PROLIFERATION. | |||
</pre> | |||
===Post-TURP granuloma present=== | |||
<pre> | |||
PROSTATE TISSUE, TRANSURETHRAL RESECTION OF THE PROSTATE (TURP): | |||
- BENIGN PROSTATIC TISSUE WITH GLANDULAR AND STROMAL PROLIFERATION WITH | |||
PROMINENT BLOOD VESSELS AND SQUAMOUS METAPLASIA. | |||
- PALISADING GRANULOMA WITH NECROTIC CORE, SEE COMMENT. | |||
- UROTHELIAL MUCOSA WITH A MILD INFLAMMATORY INFILTRATE. | |||
- NEGATIVE FOR MALIGNANCY. | |||
COMMENT: | |||
This is morphologically consistent with a post-TURP granuloma. | |||
</pre> | |||
==See also== | |||
*[[Prostate gland]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Prostate gland]] | |||
[[Category:Diagnosis]] | |||