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Difference between revisions of "Adenocarcinoma of the uterine cervix"
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Adenocarcinoma of the uterine cervix (view source)
Revision as of 03:47, 22 February 2014
, 03:47, 22 February 2014no edit summary
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'''Adenocarcinoma of the uterine cervix''' is a relative uncommon form of cervical [[cancer]]. Like the more common [[squamous cell carcinoma of the cervix]], it is associated strongly with the [[human papilloma virus]]. | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Cervical_adenocarcinoma_-_high_mag.jpg | |||
| Width = | |||
| Caption = Cervical adenocarcinoma. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = | |||
| Subtypes = | |||
| LMDDx = [[microglandular hyperplasia]], [[endocervical adenocarcinoma in situ]], metastatic [[adenocarcinoma]] (e.g. [[endometrioid endometrial carcinoma]], [[serous endometrial carcinoma]], [[colorectal adenocarcinoma]]), [[villoglandular adenocarcinoma]], [[glassy cell carcinoma]], [[clear cell carcinoma]] of the cervix | |||
| Stains = | |||
| IHC = p16 +ve, CEA +ve, vimentin -ve, ER -ve, PR -ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[uterine cervix]] - endocervical canal | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = fairly good | |||
| Other = | |||
| ClinDDx = other cervical tumours | |||
| Tx = radical trachelectomy or radical hysterectomy | |||
}} | |||
'''Adenocarcinoma of the uterine cervix''' is a relative uncommon form of cervical [[cancer]]. Like the more common [[squamous cell carcinoma of the uterine cervix|squamous cell carcinoma]], it is associated strongly with the [[human papilloma virus]]. | |||
It is also known as '''endocervical adenocarcinoma''' and '''cervical adenocarcinoma'''. | It is also known as '''endocervical adenocarcinoma''' and '''cervical adenocarcinoma'''. | ||
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==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Cells with moderate cytoplasm, typically with basally stratfied nuclei. | |||
*Cytologic changes: | |||
**Nuclear hyperchromasia. | |||
**Nuclear pseudostratification. | |||
**Nuclear enlargement. | |||
*Stromal changes - "[[desmoplastic stroma]]/[[desmoplastic reaction]]". | *Stromal changes - "[[desmoplastic stroma]]/[[desmoplastic reaction]]". | ||
**Fibrosis/streaming cells. | **Fibrosis/streaming cells. | ||
*Gland fusion. | *Abnormal architecture: | ||
*Glands too deep -- very fuzzy criterion. | **Gland fusion. | ||
**Glands too deep -- very fuzzy criterion. | |||
Notes: | Notes: | ||