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Squamous cell carcinoma of the esophagus (view source)
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'''Squamous cell carcinoma of the esophagus''' is a relatively uncommon form of esophageal cancer. | |||
It is also known as '''esophageal squamous cell carcinoma''', abbreviated '''esophageal SCC'''. | |||
''Squamous cell carcinoma'', also ''squamous carcinoma'', is discussed in general terms in the ''[[squamous cell carcinoma]]'' article. | |||
==General== | |||
*Like squamous cell carcinoma elsewhere. | |||
Risk factors:<ref name=Ref_APBR104>{{Ref APBR|104 Q1}}</ref> | |||
*[[Ethanol abuse|Alcohol consumption]]. | |||
*[[Smoking|Tobacco use]]. | |||
*Food with nitrosamines. | |||
*Burning-hot beverages. | |||
Note: | |||
*Reflux is ''not'' a risk factor for esophageal SCC. | |||
**It is a risk factor indirectly for [[esophageal adenocarcinoma]]. | |||
==Microscopic== | |||
:See ''[[Squamous carcinoma]]''. | |||
Note: | |||
*Just to make things confusing, the ''Staging'' of early SCC differs from that of early adenocarcinoma! | |||
DDx: | |||
*[[Squamous dysplasia of the esophagus]]. | |||
===Images=== | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544238/figure/fig08/ Carcinoma in situ (nih.gov)].<ref name=pmid23330004>{{Cite journal | last1 = Terada | first1 = T. | title = A clinicopathologic study of esophageal 860 benign and malignant lesions in 910 cases of consecutive esophageal biopsies. | journal = Int J Clin Exp Pathol | volume = 6 | issue = 2 | pages = 191-8 | month = | year = 2013 | doi = | PMID = 23330004 }}</ref> | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544238/figure/fig09/ Squamous cell carcinoma of the esophagus (nih.gov)]. | |||
==Sign out== | |||
<pre> | |||
ESOPHGAUS, BIOPSY: | |||
- INVASIVE SQUAMOUS CELL CARCINOMA, KERATINIZING, MODERATELY DIFFERENTIATED. | |||
COMMENT: | |||
Benign squamous epithelium at least partially overlies the invasive squamous | |||
cell carcinoma; this may mask the true extent of the lesion on endoscopy. | |||
</pre> | |||
===Micro=== | |||
The sections show a squamous mucosa with focal moderate atypia of the squamous cells, | |||
keratinization and easily identified mitotic figures. The atypical cells are partially | |||
covered by benign squamous cells, and there is a very sharp transition between the cells | |||
with atypia and those without. The atypical squamous cells extend into the subepithelial tissue in irregularly shaped nests and cords. A small amount of benign muscle is present. | |||
==See also== | |||
*[[Esophagus]]. | |||
*[[Squamous cell carcinoma]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Esophagus]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||