|
|
Line 569: |
Line 569: |
| ==Squamous cell carcinoma of the esophagus== | | ==Squamous cell carcinoma of the esophagus== |
| *[[AKA]] ''esophageal squamous cell carcinoma'', abbreviated ''esophageal SCC''. | | *[[AKA]] ''esophageal squamous cell carcinoma'', abbreviated ''esophageal SCC''. |
| {{Main|Squamous carcinoma}} | | {{Main|Squamous cell carcinoma of the esophagus}} |
| ===General===
| |
| *Like squamous cell carcinoma elsewhere.
| |
| | |
| Risk factors:<ref name=Ref_APBR104>{{Ref APBR|104 Q1}}</ref>
| |
| *[[Ethanol abuse|Alcohol consumption]].
| |
| *[[Smoking|Tobacco use]].
| |
| *Food with nitrosamines.
| |
| *Burning-hot beverages.
| |
| | |
| Note:
| |
| *Reflux is ''not'' a risk factor for esophageal SCC.
| |
| | |
| ===Microscopic===
| |
| :See ''[[Squamous carcinoma]]''.
| |
| | |
| Note:
| |
| *Just to make things confusing, the ''Staging'' of early SCC differs from that of early adenocarcinoma!
| |
| | |
| DDx:
| |
| *[[Squamous dysplasia of the esophagus]].
| |
| | |
| ====Images====
| |
| *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544238/figure/fig08/ Carcinoma in situ (nih.gov)].<ref name=pmid23330004>{{Cite journal | last1 = Terada | first1 = T. | title = A clinicopathologic study of esophageal 860 benign and malignant lesions in 910 cases of consecutive esophageal biopsies. | journal = Int J Clin Exp Pathol | volume = 6 | issue = 2 | pages = 191-8 | month = | year = 2013 | doi = | PMID = 23330004 }}</ref>
| |
| *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544238/figure/fig09/ Squamous cell carcinoma of the esophagus (nih.gov)].
| |
| | |
| ===Sign out===
| |
| <pre>
| |
| ESOPHGAUS, BIOPSY:
| |
| - INVASIVE SQUAMOUS CELL CARCINOMA, KERATINIZING, MODERATELY DIFFERENTIATED.
| |
| | |
| COMMENT:
| |
| Benign squamous epithelium at least partially overlies the invasive squamous
| |
| cell carcinoma; this may mask the true extent of the lesion on endoscopy.
| |
| </pre>
| |
| | |
| ====Micro====
| |
| The sections show a squamous mucosa with focal moderate atypia of the squamous cells,
| |
| keratinization and easily identified mitotic figures. The atypical cells are partially
| |
| covered by benign squamous cells, and there is a very sharp transition between the cells
| |
| with atypia and those without. The atypical squamous cells extend into the subepithelial tissue in irregularly shaped nests and cords. A small amount of benign muscle is present.
| |
|
| |
|
| ==Esophageal adenocarcinoma== | | ==Esophageal adenocarcinoma== |