48,830
edits
Difference between revisions of "Lhermitte-Duclos disease"
Jump to navigation
Jump to search
Lhermitte-Duclos disease (view source)
Revision as of 03:52, 17 February 2014
, 03:52, 17 February 2014split out
(redirect) |
(split out) |
||
| Line 1: | Line 1: | ||
'''Lhermitte-Duclos_disease''', abbreviated '''LDD''', is a rare [[neuropathology]]. | |||
It is also known as '''dysplastic cerebellar gangliocytoma'''<ref name=pmid20060133>{{Cite journal | last1 = Yağci-Küpeli | first1 = B. | last2 = Oguz | first2 = KK. | last3 = Bilen | first3 = MA. | last4 = Yalçin | first4 = B. | last5 = Akalan | first5 = N. | last6 = Büyükpamukçu | first6 = M. | title = An unusual cause of posterior fossa mass: Lhermitte-Duclos disease. | journal = J Neurol Sci | volume = 290 | issue = 1-2 | pages = 138-41 | month = Mar | year = 2010 | doi = 10.1016/j.jns.2009.12.010 | PMID = 20060133 }}</ref> and '''dysplastic gangliocytoma of the cerebellum'''. | |||
==General== | |||
*Cerebellar lesion. | |||
*May be associated with [[Cowden syndrome]].<ref name=omim158350>{{OMIM|158350}}</ref> | |||
==Microscopic== | |||
Features:<ref>URL: [http://path.upmc.edu/cases/case472.html http://path.upmc.edu/cases/case472.html]. Accessed on: 21 January 2012.</ref> | |||
*The outer (molecular) layer has increased cellularity. | |||
*Purkinje cells absent.<ref name=pmid20060133/> | |||
*Large (polygonal) cells with round nuclei and prominent nucleoli in the inner (granular) layer - '''key feature'''. | |||
*+/-Microcalcifications. | |||
Images: | |||
*[http://path.upmc.edu/cases/case472.html LDD - several images (upmc.edu)]. | |||
==See also== | |||
*[[Neuropathology tumours]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Neuropathology tumours]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||