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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Collagenous_spherulosis_-_very_high_mag.jpg | |||
| Width = | |||
| Caption = Collagenous spherulosis. [[H&E stain]]. | |||
| Synonyms = mucinous spherulosis, spherulosis | |||
| Micro = tubular/cribriform architecture with intratubular eosinophilic material (classical arranged like the spokes of a wheel ("radial spikes"), granules ~ 1-2 micrometers), | |||
no mitotic activity, epithelial & myoepithelial - like benign breast | |||
| Subtypes = | |||
| LMDDx = [[atypical ductal hyperplasia]], [[cribriform DCIS]], [[adenoid cystic carcinoma of the breast]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[breast]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = usu. asymptomatic | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = none required, usu. incidental finding | |||
}} | |||
'''Collagenous spherulosis''' is a benign change of the [[breast]] that can be confused for a malignancy. | '''Collagenous spherulosis''' is a benign change of the [[breast]] that can be confused for a malignancy. | ||
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