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Difference between revisions of "Nipple adenoma"
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'''Nipple adenoma''' is a benign pathology of the [[breast]]. | |||
It is also known as '''nipple duct adenoma''', '''nipple adenoma of breast''', '''adenoma of the nipple''' and '''florid papillomatosis of the nipple'''.<ref name=pmid22342578>{{Cite journal | last1 = Boutayeb | first1 = S. | last2 = Benomar | first2 = S. | last3 = Sbitti | first3 = Y. | last4 = Harroudi | first4 = T. | last5 = Hassam | first5 = B. | last6 = Errihani | first6 = H. | title = Nipple adenoma in a man: An unusual case report. | journal = Int J Surg Case Rep | volume = 3 | issue = 5 | pages = 190-2 | month = | year = 2012 | doi = 10.1016/j.ijscr.2011.05.008 | PMID = 22342578 }}</ref> | |||
==General== | |||
*Rare. | |||
*Reported in men.<ref name=pmid22342578/> | |||
Clinical DDx: | |||
*[[Paget's disease of the breast]].<ref name=pmid13904317>{{Cite journal | last1 = HANDLEY | first1 = RS. | last2 = THACKRAY | first2 = AC. | title = Adenoma of nipple. | journal = Br J Cancer | volume = 16 | issue = | pages = 187-94 | month = Jun | year = 1962 | doi = | PMID = 13904317 | PMC = 2070922 | url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2070922/?tool=pubmed }}</ref> | |||
==Microscopic== | |||
Features: | |||
*Proliferation of epithelial and myoepithelial elements that extends into the breast stroma.<ref name=pmid2123505>{{Cite journal | title = Adenoma of Nipple. | journal = Br Med J | volume = 1 | issue = 5330 | pages = 563 | month = Mar | year = 1963 | doi = | PMID = 20789667 | PMC = 2123505 | url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2123505/?page=1 }}</ref> | |||
Notes: | |||
*Not encapsulated.<ref name=pmid2123505/> | |||
*Lacks true fibrovascular cores.<ref>URL: [http://surgpathcriteria.stanford.edu/breast/nippleadenoma/printable.html http://surgpathcriteria.stanford.edu/breast/nippleadenoma/printable.html]. Accessed on: 6 August 2011.</ref> | |||
*Focal necrosis may be present.<ref name=Ref_APBR307>{{Ref APBR|307 Q16}}</ref> | |||
DDx: | |||
*[[Intraductal papilloma]]. | |||
**Found within the duct '''not''' the stroma. | |||
**Often deeper - one should '''not''' see skin in the histologic section. | |||
===Images=== | |||
<gallery> | |||
Image:Nipple_adenoma_-_low_mag.jpg | Nipple adenoma - low mag. (WC/Nephron) | |||
Image:Nipple_adenoma_-_very_high_mag.jpg | Nipple adenoma - very high mag. (WC/Nephron) | |||
</gallery> | |||
www: | |||
*[http://www.breastpathology.info/sub-pages-benign-prolif/florid-papillomatosis-ex1-1.html Florid papillomatosis of the nipple - several images (breastpathology.info)]. | |||
==See also== | |||
*[[Breast pathology]]. | |||
*[[Intraductal papilloma]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Breast pathology]] | |||