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| ==Brenner tumour== | | ==Brenner tumour== |
| ===General===
| | {{Main|Brenner tumour}} |
| *Fits into the ''transistional cell tumours'' category - in the surface epithelial group of ovarian tumours.
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| ====Epidemiology====
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| *Mostly benign clinical course.
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| *Thought to arise from [[Walthard cell rest]].
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| *Frequently an incidental finding, i.e. oophorectomy was done for another reason.
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| *May be malignant.
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| ===Gross===
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| Features:<ref name=pmid21897739>{{Cite journal | last1 = Borah | first1 = T. | last2 = Mahanta | first2 = RK. | last3 = Bora | first3 = BD. | last4 = Saikia | first4 = S. | title = Brenner tumor of ovary: An incidental finding. | journal = J Midlife Health | volume = 2 | issue = 1 | pages = 40-1 | month = Jan | year = 2011 | doi = 10.4103/0976-7800.83273 | PMID = 21897739 |PMC = 3156501}}</ref>
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| *Classically solid, well-circumscribed, light yellow.
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| *May be cystic.
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| Note:
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| *Borderline tumours classically solid and cystic with papillary projections into the cystic component.<ref name=pmid21897739/>
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| ===Microscopic===
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| Features:
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| *Nests of transitional epithelium with cells that have:<ref name=Ref_PBoD1098>{{Ref PBoD|1098}}</ref>
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| **A "[[coffee bean nucleus]]".
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| ***Elliptical shape (nucleus).
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| ***Nuclear grooves.<ref name=pathout_brenner>URL: [http://www.pathologyoutlines.com/ovarytumor.html#brennergen http://www.pathologyoutlines.com/ovarytumor.html#brennergen]. Accessed on: 8 February 2011.</ref>
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| ***Distinct nucleoli.
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| **Moderate-to-abundant gray/pale cytoplasm.
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| *Dense fibrous stroma around nests.
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| Notes:
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| *Main DDx of Coffee bean nucleus = [[granulosa cell tumour]].
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| *Stromal component may be predominant.
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| DDx:
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| *[[Ovarian fibroma]].
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| *[[Thecoma]].
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| ====Images====
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| <gallery>
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| Image:Brenner tumour high mag cropped.jpg | BT - cropped - high mag. (WC)
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| Image:Brenner tumour high mag.jpg | BT - high mag. (WC)
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| Image:Brenner tumour intermed mag.jpg | BT - intermed. mag. (WC)
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| </gallery>
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| =Germ cell tumours= | | =Germ cell tumours= |