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The '''Brenner tumour''' is an [[ovarian tumour]] in the epithelial group of ovarian tumours. | |||
==General== | |||
*Fits into the ''transistional cell tumours'' category - in the surface epithelial group of ovarian tumours. | |||
===Epidemiology=== | |||
*Mostly benign clinical course. | |||
*Thought to arise from [[Walthard cell rest]]. | |||
*Frequently an incidental finding, i.e. oophorectomy was done for another reason. | |||
*May be malignant. | |||
==Gross== | |||
Features:<ref name=pmid21897739>{{Cite journal | last1 = Borah | first1 = T. | last2 = Mahanta | first2 = RK. | last3 = Bora | first3 = BD. | last4 = Saikia | first4 = S. | title = Brenner tumor of ovary: An incidental finding. | journal = J Midlife Health | volume = 2 | issue = 1 | pages = 40-1 | month = Jan | year = 2011 | doi = 10.4103/0976-7800.83273 | PMID = 21897739 |PMC = 3156501}}</ref> | |||
*Classically solid, well-circumscribed, light yellow. | |||
*May be cystic. | |||
Note: | |||
*Borderline tumours classically solid and cystic with papillary projections into the cystic component.<ref name=pmid21897739/> | |||
==Microscopic== | |||
Features: | |||
*Nests of transitional epithelium with cells that have:<ref name=Ref_PBoD1098>{{Ref PBoD|1098}}</ref> | |||
**A "[[coffee bean nucleus]]". | |||
***Elliptical shape (nucleus). | |||
***Nuclear grooves.<ref name=pathout_brenner>URL: [http://www.pathologyoutlines.com/ovarytumor.html#brennergen http://www.pathologyoutlines.com/ovarytumor.html#brennergen]. Accessed on: 8 February 2011.</ref> | |||
***Distinct nucleoli. | |||
**Moderate-to-abundant gray/pale cytoplasm. | |||
*Dense fibrous stroma around nests. | |||
Notes: | |||
*Main DDx of Coffee bean nucleus = [[granulosa cell tumour]]. | |||
*Stromal component may be predominant. | |||
DDx: | |||
*[[Ovarian fibroma]]. | |||
*[[Thecoma]]. | |||
===Images=== | |||
<gallery> | |||
Image:Brenner tumour high mag cropped.jpg | BT - cropped - high mag. (WC) | |||
Image:Brenner tumour high mag.jpg | BT - high mag. (WC) | |||
Image:Brenner tumour intermed mag.jpg | BT - intermed. mag. (WC) | |||
</gallery> | |||
==See also== | |||
*[[Ovarian tumours]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Ovarian tumours]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||