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m (→Steatosis of the liver: to 'marked') |
m (→Fibrosis: re-write chickenwire) |
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Line 288: | Line 288: | ||
*More collagen than there should be. | *More collagen than there should be. | ||
*Assessment of fibrosis is based on the trichrome stain. | *Assessment of fibrosis is based on the trichrome stain. | ||
**Reticulin may be somewhat helpful | **Reticulin may be somewhat helpful. | ||
***The normal reticulin pattern is chicken wire-like; in early pre-cirrhosis (Grade 1-2) the chicken wire is collapsed/flattened. | |||
TGH uses ''Laennec fibrosis''; named after French chest physician.<ref name=pmid3304599>Why does cirrhosis belong to Laennec? Duffin JM. CMAJ. 1987 Sep 1;137(5):393-6. PMID 3304599. URL: [http://www.pubmedcentral.nih.gov/pagerender.fcgi?artid=1492806&pageindex=4 http://www.pubmedcentral.nih.gov/pagerender.fcgi?artid=1492806&pageindex=4]</ref> | TGH uses ''Laennec fibrosis''; named after French chest physician.<ref name=pmid3304599>Why does cirrhosis belong to Laennec? Duffin JM. CMAJ. 1987 Sep 1;137(5):393-6. PMID 3304599. URL: [http://www.pubmedcentral.nih.gov/pagerender.fcgi?artid=1492806&pageindex=4 http://www.pubmedcentral.nih.gov/pagerender.fcgi?artid=1492806&pageindex=4]</ref> |
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