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There is also a ''[[Paget disease of the bone]]'' - just to make things confusing. This is dealt with in the ''[[bone]]'' article and has nothing (from a pathologic perspective) to do with the Paget disease discussed in this article | There is also a ''[[Paget disease of the bone]]'' - just to make things confusing. This is dealt with in the ''[[bone]]'' article and has nothing (from a pathologic perspective) to do with the Paget disease discussed in this article | ||
==General== | |||
*Usually not associated with malignancy, unlike the ''Paget disease of the breast'' - '''important difference'''. | *Usually not associated with malignancy, unlike the ''Paget disease of the breast'' - '''important difference'''. | ||
*Classically seen in the [[vulva]]. | *Classically seen in the [[vulva]]. | ||
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*Pruritis. | *Pruritis. | ||
==Gross== | |||
*Erythema. | *Erythema. | ||
==Microscopic== | |||
Features: | Features: | ||
*Epitheliod morphology (round/ovoid). | *Epitheliod morphology (round/ovoid). | ||
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*Large nucleoli. | *Large nucleoli. | ||
Images | ===Images=== | ||
*[http://commons.wikimedia.org/wiki/File:Extramammary_Paget_disease_-_low_mag.jpg Paget disease - low mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Extramammary_Paget_disease_-_low_mag.jpg Paget disease - low mag. (WC)]. | ||
*[http://commons.wikimedia.org/wiki/File:Extramammary_Paget_disease_-_high_mag.jpg Paget disease - high mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Extramammary_Paget_disease_-_high_mag.jpg Paget disease - high mag. (WC)]. | ||
===DDx=== | |||
*Benign Toker cell hyperplasia. | *Benign Toker cell hyperplasia. | ||
*[[Malignant melanoma]]. | *[[Malignant melanoma]]. | ||
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==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Dermatopathology]] | [[Category:Dermatopathology]] | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Gynecologic pathology]] | [[Category:Gynecologic pathology]] |
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