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==Retinoblastoma== | ==Retinoblastoma== | ||
===General=== | |||
*Rare. | *Rare. | ||
*Malignant. | *Malignant. | ||
*May be familial.<ref name=pmid20687510> | *May be familial.<ref name=pmid20687510>{{cite journal |author=Lohmann D |title=Retinoblastoma |journal=Adv. Exp. Med. Biol. |volume=685 |issue= |pages=220–7 |year=2010 |pmid=20687510 |doi= |url=}}</ref> | ||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*[[Small round cell tumour]]. | *[[Small round cell tumour]]. | ||
*Flexner-Wintersteiner rosette. | |||
**Rosette with empty centre (donut hole).<ref name=pmid16551982>{{cite journal |author=Wippold FJ, Perry A |title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes |journal=AJNR Am J Neuroradiol |volume=27 |issue=3 |pages=488–92 |year=2006 |month=March |pmid=16551982 |doi= |url=}}</ref> | |||
***DDx of this feature: pineoblastomas, medulloepitheliomas. | |||
Image: | Image: | ||
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==References== | ==References== | ||
{{Reflist}} | {{Reflist|2}} | ||
[[Category:Weird stuff]] | [[Category:Weird stuff]] |
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