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Difference between revisions of "Neurodegenerative diseases"
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Neurodegenerative diseases (view source)
Revision as of 20:10, 20 November 2010
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==Multiple system atrophy== | ==Multiple system atrophy== | ||
===General=== | |||
Clinical findings variable: | Clinical findings variable: | ||
*Parkinsonism (stiatonigral degeneration). | *Parkinsonism (stiatonigral degeneration). | ||
*Ataxia (olivo-panto-cerebellar degeneration). | *Ataxia (olivo-panto-cerebellar degeneration). | ||
===Microscopic=== | |||
*Alpha-synuclein-rich glial cytoplasmic inclusions | Features: | ||
*Alpha-synuclein-rich glial cytoplasmic inclusions (finding at autopsy).<ref name=pmid18825660>{{Cite journal | last1 = Wenning | first1 = GK. | last2 = Stefanova | first2 = N. | last3 = Jellinger | first3 = KA. | last4 = Poewe | first4 = W. | last5 = Schlossmacher | first5 = MG. | title = Multiple system atrophy: a primary oligodendrogliopathy. | journal = Ann Neurol | volume = 64 | issue = 3 | pages = 239-46 | month = Sep | year = 2008 | doi = 10.1002/ana.21465 | PMID = 18825660 }}</ref> | |||
**Inclusions in oligodendrocytes.<ref>MUN. 16 November 2010.</ref> | **Inclusions in oligodendrocytes.<ref>MUN. 16 November 2010.</ref> | ||