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Difference between revisions of "Endometrioid endometrial carcinoma"
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Endometrioid endometrial carcinoma (view source)
Revision as of 03:19, 22 January 2014
, 03:19, 22 January 2014tewak
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'''Endometrioid endometrial carcinoma''' is a type of [[endometrial carcinoma]]. | '''Endometrioid endometrial carcinoma''' is a type of [[endometrial carcinoma]]. | ||
It is also known as '''endometrioid endometrial adenocarcinoma'''. | |||
==General== | ==General== | ||
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**Typical patient is [[obese]]. | **Typical patient is [[obese]]. | ||
==Gross== | |||
*Thickened endometrium. | *Thickened endometrium. | ||
==Microscopic== | |||
Features: | Features: | ||
*Atypical (ovoid) glands with - one of the following four:<ref name=Ref_GP239>{{Ref GP|239}}</ref><ref name=pmid7074572>{{Cite journal | last1 = Kurman | first1 = RJ. | last2 = Norris | first2 = HJ. | title = Evaluation of criteria for distinguishing atypical endometrial hyperplasia from well-differentiated carcinoma. | journal = Cancer | volume = 49 | issue = 12 | pages = 2547-59 | month = Jun | year = 1982 | doi = | PMID = 7074572 }}</ref><ref>URL: [http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Endometrium_11protocol.pdf http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Endometrium_11protocol.pdf]. Accessed on: 12 January 2012.</ref> | *Atypical (ovoid) glands with - one of the following four:<ref name=Ref_GP239>{{Ref GP|239}}</ref><ref name=pmid7074572>{{Cite journal | last1 = Kurman | first1 = RJ. | last2 = Norris | first2 = HJ. | title = Evaluation of criteria for distinguishing atypical endometrial hyperplasia from well-differentiated carcinoma. | journal = Cancer | volume = 49 | issue = 12 | pages = 2547-59 | month = Jun | year = 1982 | doi = | PMID = 7074572 }}</ref><ref>URL: [http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Endometrium_11protocol.pdf http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Endometrium_11protocol.pdf]. Accessed on: 12 January 2012.</ref> | ||
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*[[Clear cell carcinoma of the endometrium]] - esp. when clear cells present. | *[[Clear cell carcinoma of the endometrium]] - esp. when clear cells present. | ||
===Images=== | |||
<gallery> | <gallery> | ||
Image:Endometrioid endometrial adenocarcinoma low mag.jpg | EEA - low mag. (WC) | Image:Endometrioid endometrial adenocarcinoma low mag.jpg | EEA - low mag. (WC) | ||
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*[http://www.diagnosticpathology.org/content/2/1/40/figure/F1?highres=y Squamous morule with dyskeratotic cell (diagnosticpathology.org)]. | *[http://www.diagnosticpathology.org/content/2/1/40/figure/F1?highres=y Squamous morule with dyskeratotic cell (diagnosticpathology.org)]. | ||
==IHC== | |||
*Vimentin +ve. | *Vimentin +ve. | ||
*ER +ve. | *ER +ve. | ||
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*CEA -ve. | *CEA -ve. | ||
==Sign out== | |||
<pre> | <pre> | ||
ENDOMETRIUM, BIOPSY: | ENDOMETRIUM, BIOPSY: | ||
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</pre> | </pre> | ||
===Micro=== | |||
The sections show endometrium with complex, fused and cribriform glands with scant intervening stroma over a region measuring greater than 2.1 millimetres. Focally, a desmoplastic stroma is also identified. No nuclear atypia is appreciated. | The sections show endometrium with complex, fused and cribriform glands with scant intervening stroma over a region measuring greater than 2.1 millimetres. Focally, a desmoplastic stroma is also identified. No nuclear atypia is appreciated. | ||
===Endocervical versus endometrial - biopsy=== | |||
The foamy histiocytes in the stroma and lack of desmoplasia slightly favour an endometrial origin; however, the lesion would be best classified with an excisional specimen and in conjunction with the clinical impression. | The foamy histiocytes in the stroma and lack of desmoplasia slightly favour an endometrial origin; however, the lesion would be best classified with an excisional specimen and in conjunction with the clinical impression. | ||
==See also== | ==See also== | ||
*[[Endometrial carcinoma | *[[Endometrial carcinoma]]. | ||
*[[Endometrial hyperplasia]]. | |||
==References== | ==References== | ||