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Uterine cervix with atrophic changes (view source)
Revision as of 03:50, 18 January 2014
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'''Uterine cervix with atrophic changes''' is relatively common and is important to recognize as it can mimic [[HSIL]]. | |||
It is also known as '''atrophy of the uterine cervix''', '''cervical atrophy''', '''atrophy of the cervix''' and '''cervix with atrophic changes'''. | |||
==General== | |||
*Common. | |||
*Post-menupausal. | |||
*Important to recognize and differentiate from [[HSIL]]. | |||
==Microscopic== | |||
Features: | |||
*Cells smaller. | |||
*Cytoplasm grey/blue. | |||
*No "dancing"/"sparkling" chromatin. | |||
*No mitoses. | |||
DDx: | |||
*[[HSIL]]. | |||
===Images=== | |||
www: | |||
*[http://nih.techriver.net/view.php?patientId=93 Atrophic cervix (nih.techriver.net)]. | |||
*[http://www.flickriver.com/photos/euthman/3884912676/ Atrophic cervix (flickriver.com/euthman)]. | |||
*[http://www.eurocytology.eu/static/eurocytology/image/mod1newa.jpg Atrophic changes in the vagina (eurocytology.eu)].<ref>URL: [http://www.eurocytology.eu/static/eurocytology/TUR/cervical/LP1ContentLcontC.html http://www.eurocytology.eu/static/eurocytology/TUR/cervical/LP1ContentLcontC.html]. Accessed on: 13 December 2013.</ref> | |||
==IHC== | |||
*p16 -ve. | |||
*Ki-67 rare basal cells. | |||
==Sign out== | |||
<pre> | |||
UTERINE CERVIX, BIOPSY: | |||
- SQUAMOUS MUCOSA WITH ATROPHIC CHANGES. | |||
- BENIGN ENDOCERVICAL EPITHELIUM. | |||
- NEGATIVE FOR DYSPLASIA. | |||
COMMENT: | |||
A p16 immunostain is negative. A Ki-67 immunostain marks rare basal cells. | |||
</pre> | |||
==See also== | |||
*[[Uterine cervix]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Uterine cervix]] | |||
[[Category:Diagnosis]] | |||