Difference between revisions of "Pancreas"

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Pancreas (view source)

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→‎Serous cystadenoma of the pancreas: split out
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==Serous cystadenoma of the pancreas==
==Serous cystadenoma of the pancreas==
*[[AKA]] ''serous microcystic adenoma'',<ref name=Ref_Sternberg4_1630>{{Ref Sternberg4|1630}}</ref> [[AKA]] ''pancreatic serous cystadenoma''.
*[[AKA]] ''serous microcystic adenoma'',<ref name=Ref_Sternberg4_1630>{{Ref Sternberg4|1630}}</ref> [[AKA]] ''pancreatic serous cystadenoma''.
===General===
{{Serous cystadenoma of the pancreas}}
*1-2% of all exocrine pancreatic tumours.
*Female > male.
*Mean age 66 years.
*Truly benign with no malignant potenial.
*May be part of [[von Hippel-Lindau syndrome]].
 
Management:
*Observe or resect.
 
===Gross===
Features:
*Classically has a characteristic central scar.<ref name=pmid15888617>{{cite journal |author=Kim YH, Saini S, Sahani D, Hahn PF, Mueller PR, Auh YH |title=Imaging diagnosis of cystic pancreatic lesions: pseudocyst versus nonpseudocyst |journal=Radiographics |volume=25 |issue=3 |pages=671–85 |year=2005 |pmid=15888617 |doi=10.1148/rg.253045104 |url=http://radiographics.rsna.org/content/25/3/671.abstract}}</ref>
*Bosulated surface.
*Lobulated.
*No (macroscopic) cysts apparent on gross.
*Location: 50-70% occur in the body and tail.
*Size: average size 11 cm.
 
Radiologic appearance:
*Honey comb-like appearance.
*Well demarcated border - may be described as a "coin lesion".
 
Image:
*[http://www.joplink.net/prev/200905/25_fig06.jpg Serous microcystic adenoma (joplink.net)].<ref name=pmid19454830>{{Cite journal  | last1 = Vernadakis | first1 = S. | last2 = Kaiser | first2 = GM. | last3 = Christodoulou | first3 = E. | last4 = Mathe | first4 = Z. | last5 = Troullinakis | first5 = M. | last6 = Bankfalvi | first6 = A. | last7 = Paul | first7 = A. | title = Enormous serous microcystic adenoma of the pancreas. | journal = JOP | volume = 10 | issue = 3 | pages = 332-4 | month =  | year = 2009 | doi =  | PMID = 19454830 |URL = http://www.joplink.net/prev/200905/25.html }}</ref>
 
===Microscopic===
Features:
*Cystic spaces lined by cuboidal cells.
**Glycogen rich.
**Cilia. (???)
 
DDx:
*[[Renal cell carcinoma]].
*[[Lymphangioma]].
*[[Hemangioma]].
*Oligocystic mucinous cystic tumors and pseudocysts.
**Have mucin; PAS-D could be used to demonstrate its presence.
 
Notes:
*Serous adenoma may coexist with aggressive tumours.
 
====Images====
<gallery>
Image:Pancreatic_serous_cystadenoma_-_low_mag.jpg | PSC - low mag. (WC)
Image:Pancreatic_serous_cystadenoma_-_intermed_mag.jpg | PSC - intermed. mag. (WC)
Image:Pancreatic_serous_cystadenoma_-_high_mag.jpg | PSC - high mag. (WC)
Image:Pancreatic_serous_cystadenoma_-_very_high_mag.jpg | PSC - very high mag. (WC)
</gallery>
 
===Stains===
*PAS +ve.
*PASD -ve.


==Mucinous cystic neoplasms of the pancreas==
==Mucinous cystic neoplasms of the pancreas==
Michael
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