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Difference between revisions of "Serous carcinoma of the ovary"
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Serous carcinoma of the ovary (view source)
Revision as of 20:24, 13 January 2014
, 20:24, 13 January 2014no edit summary
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*PAX2 +ve. | *PAX2 +ve. | ||
**Usually -ve in [[malignant mesothelioma]].<ref name=pmid22498671>{{Cite journal | last1 = Gao | first1 = FF. | last2 = Krasinskas | first2 = AM. | last3 = Chivukula | first3 = M. | title = Is PAX2 a reliable marker in differentiating diffuse malignant mesotheliomas of peritoneum from serous carcinomas of müllerian origin? | journal = Appl Immunohistochem Mol Morphol | volume = 20 | issue = 3 | pages = 272-6 | month = May | year = 2012 | doi = 10.1097/PAI.0b013e3182366531 | PMID = 22498671 }}</ref> | **Usually -ve in [[malignant mesothelioma]].<ref name=pmid22498671>{{Cite journal | last1 = Gao | first1 = FF. | last2 = Krasinskas | first2 = AM. | last3 = Chivukula | first3 = M. | title = Is PAX2 a reliable marker in differentiating diffuse malignant mesotheliomas of peritoneum from serous carcinomas of müllerian origin? | journal = Appl Immunohistochem Mol Morphol | volume = 20 | issue = 3 | pages = 272-6 | month = May | year = 2012 | doi = 10.1097/PAI.0b013e3182366531 | PMID = 22498671 }}</ref> | ||
==Sign out== | |||
<pre> | |||
A. RIGHT OVARY, BIOPSY: | |||
- SEROUS CARCINOMA, HIGH-GRADE. | |||
- PSAMMOMATOUS CALCIFICATIONS. | |||
B. OMENTUM, BIOPSY: | |||
- SEROUS CARCINOMA, HIGH-GRADE. | |||
- PSAMMOMATOUS CALCIFICATIONS. | |||
COMMENT: | |||
The morphology is compatible with a serous carcinoma (prominent | |||
nucleoli, large nuclear size variation, psammomatous calcifications). | |||
The immunostains are that of a serous carcinoma: | |||
POSITIVE: CK7, ER, PR (focal), CA-125, WT-1. | |||
NEGATIVE: CK20, p53. | |||
The ovary has multiple small tumour nodules. The status of the opposite | |||
ovary is unknown. The bulk of the tumour in the specimen provided is in | |||
the omentum. | |||
Clinical and radiologic correlation is suggested for the determination of | |||
the primary site of this serous carcinoma. | |||
</pre> | |||
==See also== | ==See also== | ||