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| Caption = Colonic pseudomembrane. [[H&E stain]]. | | Caption = Colonic pseudomembrane. [[H&E stain]]. | ||
| Synonyms = ''C. | | Synonyms = ''C. difficile colitis'' commonly used as synonym by clinicians - ''not'' the same from the same for the perspective of pathology | ||
| Micro = heaped necrotic surface epithelium (described as "volanco lesions"), [[PMN]]s in lamina propria, +/-capillary fibrin thrombi | | Micro = heaped necrotic surface epithelium (described as "volanco lesions"), [[PMN]]s in lamina propria, +/-capillary fibrin thrombi | ||
| Subtypes = | | Subtypes = | ||
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| Other = ''C. difficile'' toxin test positive (may be negative) | | Other = ''C. difficile'' toxin test positive (may be negative) | ||
| ClinDDx = | | ClinDDx = | ||
| Tx = dependent on underlying cause, antibiotics in ''C. | | Tx = dependent on underlying cause, antibiotics in ''C. difficile'' - occasionally surgical resection | ||
}} | }} | ||
'''Pseudomembranous colitis''' an inflammation of the [[colon]] ([[colitis]]) with a characteristic endoscopic/gross appearance. It is closely associated with ''C. | '''Pseudomembranous colitis''' an inflammation of the [[colon]] ([[colitis]]) with a characteristic endoscopic/gross appearance. It is closely associated with ''C. difficile'' infections; however, may be seen in a number of different situations. | ||
==General== | ==General== |
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