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Difference between revisions of "Urothelial dysplasia"
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==IHC== | ==IHC== | ||
A comparison between benign, dysplasia and [[UCIS]]:<ref name=pmid12640096>{{Cite journal | last1 = Mallofré | first1 = C. | last2 = Castillo | first2 = M. | last3 = Morente | first3 = V. | last4 = Solé | first4 = M. | title = Immunohistochemical expression of CK20, p53, and Ki-67 as objective markers of urothelial dysplasia. | journal = Mod Pathol | volume = 16 | issue = 3 | pages = 187-91 | month = Mar | year = 2003 | doi = 10.1097/01.MP.0000056628.38714.5D | PMID = 12640096 }}</ref> | |||
{| class="wikitable sortable" | {| class="wikitable sortable" | ||
! Diagnosis | ! Diagnosis | ||
| Line 33: | Line 33: | ||
! p53 | ! p53 | ||
|- | |- | ||
| Benign | | Benign (reactive) | ||
| +ve | | umbrella cells +ve only | ||
| +/-basal < | | -ve <=10% of cells (+/-rare basal cells) | ||
| -ve <20% of cells (+/-weak staining) | |||
|- | |- | ||
| Urothelial dysplasia | | Urothelial dysplasia | ||
| +ve ~30% of cases | | +ve non-umbrella cells +ve (~30% of cases) | ||
| +ve ~40% of cases | | +ve >10% of cells (~40% of cases) | ||
| +ve ~70% of cases | | +ve >=20% of cells (~70% of cases) | ||
|- | |- | ||
| [[Urothelial carcinoma in situ| | | [[Urothelial carcinoma in situ|Urothelial carcinoma in situ]] (UCIS) | ||
| | | +ve non-umbrella cells (~70% of cases) | ||
| >10% ~95% of cases | | +ve >10% of cells (~95% of cases) | ||
| +ve ~80% of cases | | +ve >=20% of cells (~80% of cases) | ||
|} | |} | ||