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Difference between revisions of "Urothelial dysplasia"
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(+IHC) |
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===Images=== | ===Images=== | ||
*[http://pathology.jhu.edu/bladder/image1.cfm?case_number=10&image_number=1 Urothelial dysplasia (jhu.edu)]. | *[http://pathology.jhu.edu/bladder/image1.cfm?case_number=10&image_number=1 Urothelial dysplasia (jhu.edu)]. | ||
==IHC== | |||
Benign/dysplasia/CIS - a comparison:<ref name=pmid12640096>{{Cite journal | last1 = Mallofré | first1 = C. | last2 = Castillo | first2 = M. | last3 = Morente | first3 = V. | last4 = Solé | first4 = M. | title = Immunohistochemical expression of CK20, p53, and Ki-67 as objective markers of urothelial dysplasia. | journal = Mod Pathol | volume = 16 | issue = 3 | pages = 187-91 | month = Mar | year = 2003 | doi = 10.1097/01.MP.0000056628.38714.5D | PMID = 12640096 }}</ref> | |||
{| class="wikitable sortable" | |||
! Diagnosis | |||
! CK20 | |||
! Ki-67 | |||
! p53 | |||
|- | |||
| Benign | |||
| +ve -- umbrella cells only | |||
| +/-basal <10% | |||
| +/-basal weak | |||
|- | |||
| Urothelial dysplasia | |||
| +ve ~30% of cases | |||
| +ve ~40% of cases | |||
| +ve ~70% of cases | |||
|- | |||
| [[Urothelial carcinoma in situ|Carcinoma in situ]] | |||
| full thickness ~70% of cases | |||
| >10% ~95% of cases | |||
| +ve ~80% of cases | |||
|} | |||
==See also== | ==See also== | ||