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Difference between revisions of "Medical kidney diseases"
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Medical kidney diseases (view source)
Revision as of 06:48, 14 November 2010
, 06:48, 14 November 2010→Pathologic DDx
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*Membranoproliferative glomerulonephritis (MPGN). | *Membranoproliferative glomerulonephritis (MPGN). | ||
===Patterns - Table=== | ===Patterns - Table=== | ||
{| class="wikitable" | {| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | ||
| '''Pattern''' | | '''Pattern''' | ||
| '''Key feature''' | | '''Key feature''' | ||
| '''Other findings''' | | '''Other findings''' | ||
| '''EM''' | | '''IF & EM''' | ||
| '''Presentation''' | |||
| '''Clinical''' | | '''Clinical''' | ||
| '''Pathol. DDx''' | | '''Pathol. DDx''' | ||
| Line 238: | Line 239: | ||
|- | |- | ||
|Nodular GS | |Nodular GS | ||
| | | nodular mesangial matrix expansion | ||
| | | GBM thickening, both afferent and efferent arteriole hyalinzed | ||
| EM? | |||
| presentation? | |||
| diabetes mellitus | |||
| membranous nephropathy (?) | |||
| Image? | |||
|- | |||
|Focal segmental GS (FSGS) | |||
| focal sclerosis of glom | |||
| +/-interstitial fibrosis | |||
| EM? | |||
| nephrotic syndrome | |||
| primary FSGS, secondary FSGS; unresponsive to steroids, worse prognosis than MCD | |||
| Pathol. DDx? | |||
| Image? | |||
|- | |||
|Membranous nephropathy<br>(AKA membranous GN) | |||
| Gloms with wire loops | |||
| mesangial hypercellularity | |||
| EM? | |||
| nephrotic syndrome | |||
| hep B, hep C, carcinoma, NSAID toxicity, SLE, idiopathic | |||
| Nodular GS (?) | |||
| Image? | |||
|- | |||
|Minimal change disease (MCD) | |||
| EM changes | |||
| usu. none | |||
| EM changes | |||
| nephrotic syndrome | |||
| idiopathic vs. secondary; idiopathic responds to steroids | |||
| Pathol. DDx? | |||
| Image? | |||
|- | |||
|IgA nephropathy | |||
| +ve IF for IgA | |||
| none (?) | |||
| EM? | | EM? | ||
| mixed nephrotic/nephritic | |||
| Clinical? | | Clinical? | ||
| Pathol. DDx? | | Pathol. DDx? | ||
| Image? | | Image? | ||
|- | |- | ||
| | |Membranoproliferative GN | ||
| Key feature? | | Key feature? | ||
| Other findings? | | Other findings? | ||
| EM? | | EM? | ||
| mixed nephrotic/nephritic | |||
| Clinical? | | Clinical? | ||
| Pathol. DDx? | | Pathol. DDx? | ||
| Image? | | Image? | ||
|- | |- | ||
| | |Focal proliferative<br> glomerosclerosis (FPFS) | ||
| Key feature? | | Key feature? | ||
| Other findings? | | Other findings? | ||
| EM? | | EM? | ||
| mixed nephrotic/nephritic | |||
| Clinical? | | Clinical? | ||
| Pathol. DDx? | | Pathol. DDx? | ||
| Image? | | Image? | ||
|- | |- | ||
|Rapidly progressive GN (RPGN) | |Rapidly progressive GN (RPGN) | ||
| Line 265: | Line 305: | ||
| Other findings? | | Other findings? | ||
| EM? | | EM? | ||
| nephritic syndrome | |||
| Clinical? | | Clinical? | ||
| Pathol. DDx? | | Pathol. DDx? | ||
| Image? | | Image? | ||
|- | |- <!-- | ||
| Pattern | | Pattern | ||
| Key feature? | | Key feature? | ||
| Other findings? | | Other findings? | ||
| EM? | | EM? | ||
| Presentation? | |||
| Clinical? | | Clinical? | ||
| Pathol. DDx? | | Pathol. DDx? | ||
| Image? | | Image? --> | ||
|} | |} | ||
==Nephrotic syndrome== | ==Nephrotic syndrome== | ||