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Difference between revisions of "Necrotizing fasciitis"
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Necrotizing fasciitis (view source)
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'''Necrotizing_fasciitis''', also known as '''flesh-eating disease''', is an uncommon [[mon-malignant skin disease]] with a high mortality. | |||
It should '''''not''' to be confused with [[nodular fasciitis]]''. | |||
==General== | |||
*High mortality. | |||
*May be diagnosed at [[frozen section]].<ref name=pmid9386043>{{Cite journal | last1 = Majeski | first1 = J. | last2 = Majeski | first2 = E. | title = Necrotizing fasciitis: improved survival with early recognition by tissue biopsy and aggressive surgical treatment. | journal = South Med J | volume = 90 | issue = 11 | pages = 1065-8 | month = Nov | year = 1997 | doi = | PMID = 9386043 }}</ref> | |||
*Classically associated with ''Group A streptococcus''. | |||
Treatment: | |||
*Operative debridement. | |||
==Microscopic== | |||
Features: | |||
*Necrosis of fascia - '''key feature'''.<ref name=pmid15735411>{{Cite journal | last1 = Wong | first1 = CH. | last2 = Wang | first2 = YS. | title = The diagnosis of necrotizing fasciitis. | journal = Curr Opin Infect Dis | volume = 18 | issue = 2 | pages = 101-6 | month = Apr | year = 2005 | doi = | PMID = 15735411 | URL = http://www.sepeap.org/archivos/pdf/9859.pdf }}</ref> | |||
**[[PMN]]s and necrotic debris (amorphous grey or pink material). | |||
Note: | |||
*Fat lobules between septae may be normal. | |||
DDx: | |||
*[[Cellulitis]]. | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Necrotizing_fasciitis_-_intermed_mag.jpg Necrotizing fasciitis - intermed. mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Necrotizing_fasciitis_-_high_mag.jpg Necrotizing fasciitis - high mag. (WC)]. | |||
==See also== | |||
*[[Non-malignant skin disease]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Non-malignant skin disease]] | |||