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Difference between revisions of "Small cell lymphomas"
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(→IHC) |
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| mantle zone | | mantle zone | ||
| small | | small | ||
| CD5+, CD23-, CD43+, cyclin D1+<ref name=Ref_Lester95>{{Ref Lester|95}}</ref> | | CD5+, [[CD23]]-, CD43+, cyclin D1+<ref name=Ref_Lester95>{{Ref Lester|95}}</ref> | ||
| t(11;14)(q13;q32) BCL1/IGH<ref>URL: [http://atlasgeneticsoncology.org/Anomalies/t1114ID2021.html http://atlasgeneticsoncology.org/Anomalies/t1114ID2021.html]. Accessed on: 10 August 2010.</ref> (also IGH/BCL1<ref>URL: [http://www.wipo.int/patentscope/search/en/WO2010059499 http://www.wipo.int/patentscope/search/en/WO2010059499]. Accessed on: 26 May 2011.</ref>) | | t(11;14)(q13;q32) BCL1/IGH<ref>URL: [http://atlasgeneticsoncology.org/Anomalies/t1114ID2021.html http://atlasgeneticsoncology.org/Anomalies/t1114ID2021.html]. Accessed on: 10 August 2010.</ref> (also IGH/BCL1<ref>URL: [http://www.wipo.int/patentscope/search/en/WO2010059499 http://www.wipo.int/patentscope/search/en/WO2010059499]. Accessed on: 26 May 2011.</ref>) | ||
| aggressive, poor prognosis<ref name=pmid10583923/> | | aggressive, poor prognosis<ref name=pmid10583923/> | ||
| Line 56: | Line 56: | ||
| location ? | | location ? | ||
| small | | small | ||
| CD5+, CD23+, CD43+, cyclin D1- | | CD5+, [[CD23]]+, CD43+, cyclin D1- | ||
| trisomy 12; deletions of 11q, 13q, 17p<ref>{{Ref PCPBoD8|318}}</ref> | | trisomy 12; deletions of 11q, 13q, 17p<ref>{{Ref PCPBoD8|318}}</ref> | ||
| good prognosis / indolent course | | good prognosis / indolent course | ||
| Line 374: | Line 374: | ||
*CD20 +ve. | *CD20 +ve. | ||
*CD5 +ve. | *CD5 +ve. | ||
*CD23 +ve -- occasionally negative.<ref>URL: [http://path.upmc.edu/cases/case296/dx.html http://path.upmc.edu/cases/case296/dx.html]. Accessed on: 14 January 2012.</ref> | *[[CD23]] +ve -- occasionally negative.<ref>URL: [http://path.upmc.edu/cases/case296/dx.html http://path.upmc.edu/cases/case296/dx.html]. Accessed on: 14 January 2012.</ref> | ||
*CD43 +ve. | *CD43 +ve. | ||