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Difference between revisions of "Neurodegenerative diseases"
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Neurodegenerative diseases (view source)
Revision as of 13:50, 12 November 2010
, 13:50, 12 November 2010overview
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'''Neurodegenerative diseases''' is a big part of [[neuropathology]]. | '''Neurodegenerative diseases''' is a big part of [[neuropathology]]. | ||
==Overview== | |||
They are essentially progressive and selective neuron loss. Clinically, they are not unique. They are defined by molecular pathology.<ref name=pmid19918325>{{cite journal |author=Dickson DW |title=Neuropathology of non-Alzheimer degenerative disorders |journal=Int J Clin Exp Pathol |volume=3 |issue=1 |pages=1–23 |year=2009 |pmid=19918325 |pmc=2776269 |doi= |url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776269/?tool=pubmed}}</ref> | |||
Molecular schema of neurodegenerative disorders:<ref name=pmid19918325/> | |||
{{familytree/start}} | |||
{{familytree | | | | | | | A01 | | | | | | | | A01=Neurodegenerative<br>disorders}} | |||
{{familytree | |,|-|-|-|v|-|^|-|v|-|-|-|.| | |}} | |||
{{familytree | B01 | | B02 | | B03 | | B04 | |B01=Amyloidoses|B02=Tauopathies|B03=α-synucleinopathies|B04=TDP-43}} | |||
{{familytree/end}} | |||
==General DDx of dementia== | ==General DDx of dementia== | ||