Difference between revisions of "Neurodegenerative diseases"

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overview
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'''Neurodegenerative diseases''' is a big part of [[neuropathology]].
'''Neurodegenerative diseases''' is a big part of [[neuropathology]].
 
==Overview==
They are essentially progressive and selective neuron loss.  Clinically, they are not unique.  They are defined by molecular pathology.<ref name=pmid19918325>{{cite journal |author=Dickson DW |title=Neuropathology of non-Alzheimer degenerative disorders |journal=Int J Clin Exp Pathol |volume=3 |issue=1 |pages=1–23 |year=2009 |pmid=19918325 |pmc=2776269 |doi= |url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776269/?tool=pubmed}}</ref>
 
Molecular schema of neurodegenerative disorders:<ref name=pmid19918325/>
{{familytree/start}}                     
{{familytree  | | | | | | | A01 | | | | | | | | A01=Neurodegenerative<br>disorders}}
{{familytree  | |,|-|-|-|v|-|^|-|v|-|-|-|.| | |}}
{{familytree  | B01 | | B02 | | B03 | | B04 | |B01=Amyloidoses|B02=Tauopathies|B03=α-synucleinopathies|B04=TDP-43}}
{{familytree/end}}


==General DDx of dementia==
==General DDx of dementia==
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