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Difference between revisions of "Squamous cell carcinoma of the skin"
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Squamous cell carcinoma of the skin (view source)
Revision as of 02:31, 18 December 2013
, 02:31, 18 December 2013no edit summary
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| Micro = | | Micro = | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = | | LMDDx = [[inverted follicular keratosis]], [[Paget disease of the breast]], [[eccrine carcinoma]], [[atypical fibroxanthoma]], [[malignant melanoma]], [[leiomyosarcoma]] | ||
| Stains = | | Stains = | ||
| IHC = CK5/6 +ve, p63 +ve, K903 +ve, Ber-EP4 -ve, S-100 -ve | | IHC = CK5/6 +ve, p63 +ve, K903 +ve, Ber-EP4 -ve, S-100 -ve | ||
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***These people sign this entity as ''low grade squamous cell carcinoma, keratoacanthoma type''.<ref>RS. 17 May 2010.</ref> | ***These people sign this entity as ''low grade squamous cell carcinoma, keratoacanthoma type''.<ref>RS. 17 May 2010.</ref> | ||
==Gross== | |||
Features:<ref name=pmid15526735 >{{Cite journal | last1 = Stulberg | first1 = DL. | last2 = Crandell | first2 = B. | last3 = Fawcett | first3 = RS. | title = Diagnosis and treatment of basal cell and squamous cell carcinomas. | journal = Am Fam Physician | volume = 70 | issue = 8 | pages = 1481-8 | month = Oct | year = 2004 | doi = | PMID = 15526735 }} | |||
</ref> | |||
*Scaly patches/nodules. | |||
*Usu. erythematous. | |||
*+/-Ulceration. | |||
*"Keratin" plugs appearance. | |||
Notes: | |||
*Typically sun exposed areas. | |||
==Microscopic== | ==Microscopic== | ||
*See ''[[squamous cell carcinoma]]''. | *See ''[[squamous cell carcinoma]]''. | ||
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*>=2 mm thickness -- measured from ''granular layer'' (stratum granulosum) ''or'' ulcer base to deepest aspect. | *>=2 mm thickness -- measured from ''granular layer'' (stratum granulosum) ''or'' ulcer base to deepest aspect. | ||
*[[Lymphovascular invasion]]. | *[[Lymphovascular invasion]]. | ||
*Perineural invasion. | *[[Perineural invasion]]. | ||
*Poorly differentiated. | *Poorly differentiated. | ||