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Medical kidney diseases (view source)
Revision as of 04:39, 10 November 2010
, 04:39, 10 November 2010→Lupus nephritis
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==Lupus nephritis== | ==Lupus nephritis== | ||
===General=== | ===General=== | ||
Bread & butter of nephropathology. | *Abbreviated ''LN''. | ||
*Bread & butter of nephropathology. | |||
===Classification | ===Classification=== | ||
International Society of Nephrology/Renal Pathology Society (ISN/RPS) classification:<ref>{{cite journal |author=Weening JJ, D'Agati VD, Schwartz MM, ''et al.'' |title=The classification of glomerulonephritis in systemic lupus erythematosus revisited |journal=J. Am. Soc. Nephrol. |volume=15 |issue=2 |pages=241–50 |year=2004 |month=February |pmid=14747370 |doi= |url=http://www.nature.com/ki/journal/v55/n2/full/4490631a.html}}</ref> | International Society of Nephrology/Renal Pathology Society (ISN/RPS) classification:<ref>{{cite journal |author=Weening JJ, D'Agati VD, Schwartz MM, ''et al.'' |title=The classification of glomerulonephritis in systemic lupus erythematosus revisited |journal=J. Am. Soc. Nephrol. |volume=15 |issue=2 |pages=241–50 |year=2004 |month=February |pmid=14747370 |doi= |url=http://www.nature.com/ki/journal/v55/n2/full/4490631a.html}}</ref><ref>URL: [http://www.med.niigata-u.ac.jp/npa/Lectures/Lupus_Nephritis.htm http://www.med.niigata-u.ac.jp/npa/Lectures/Lupus_Nephritis.htm]. Accessed on: 9 November 2010.</ref> | ||
*Class I. | *Class I - minimal mesangial LN. | ||
*Class II. | *Class II - mesangial proliferative LN. | ||
*Class III. | *Class III - focal lupus nephritis; <50% of glomeruli. | ||
*Class VI. | *Class VI - diffuse segmental or global LN; >50% of glomeruli. | ||
*Class V. | *Class V - Membranous lupus nephritis. | ||
*Class IV. | *Class IV - Advanced sclerosing LN; essentially end-stage kidney. | ||
Notes: | Notes: | ||
* | *Most of the action is in Class III and Class IV. | ||
**Class I is near normal - doesn't get biopsied. | |||
**Class IV is essentially dead kidney - doesn't get biopsied. | |||
==Fabry disease== | ==Fabry disease== | ||