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Difference between revisions of "Intestinal metaplasia of the gallbladder"
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Intestinal metaplasia of the gallbladder (view source)
Revision as of 01:48, 15 December 2013
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Gallbladder with intestinal metaplasia -- intermed mag.jpg | |||
| Width = | |||
| Caption = Gallbladder with intestinal metaplasia. [[H&E stain]]. | |||
| Micro = | |||
| Subtypes = | |||
| LMDDx = gallbladder mucosa with goblet cells | |||
| Stains = [[Alcian blue stain]] +ve | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[gallbladder]] | |||
| Assdx = [[chronic cholecystitis]] | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign, increased risk of carcinoma | |||
| Other = | |||
| ClinDDx = | |||
}} | |||
'''Intestinal metaplasia of the gallbladder''' is a pathology of the gallbladder associated with an increased risk of [[gallbladder carcinoma]]. | |||
It is also known as '''gallbladder [[intestinal metaplasia]]'''. | |||
==General== | |||
Significance: | |||
*Increased risk of carcinoma.<ref name=pmid8364865/> | |||
==Gross== | |||
*No specific changes. | |||
==Microscopic== | |||
Features:<ref name=pmid2872152>{{Cite journal | last1 = Albores-Saavedra | first1 = J. | last2 = Nadji | first2 = M. | last3 = Henson | first3 = DE. | last4 = Ziegels-Weissman | first4 = J. | last5 = Mones | first5 = JM. | title = Intestinal metaplasia of the gallbladder: a morphologic and immunocytochemical study. | journal = Hum Pathol | volume = 17 | issue = 6 | pages = 614-20 | month = Jun | year = 1986 | doi = | PMID = 2872152 }}</ref> | |||
*[[Goblet cell]]s - '''key feature'''. | |||
*+/-Paneth cells.<ref name=Ref_Sternberg4_1789>{{Ref Sternberg4|1789}}</ref> | |||
Note: | |||
*Often accompanied by antral type metplasia. | |||
**Gastric antral-type epithelium - may form glands. | |||
DDx: | |||
*[[Gallbladder adenocarcinoma]]. | |||
===Images=== | |||
<gallery> | |||
Image: Gallbladder with intestinal metaplasia -- low mag.jpg | GB with IM - low mag. | |||
Image: Gallbladder with intestinal metaplasia -- intermed mag.jpg | GB with IM - intermed. mag. | |||
Image: Gallbladder with intestinal metaplasia -- high mag.jpg | GB with IM - high mag. | |||
</gallery> | |||
www: | |||
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-129-3-386-f01&doi=10.1043%2F1543-2165%282005%29129%3C386%3APPOGDA%3E2.0.CO%3B2 IM - among other things (archivesofpathology.org)].<ref name=pmid15737036/> | |||
==Sign out== | |||
<pre> | |||
GALLBLADDER, CHOLECYSTECTOMY: | |||
- INTESTINAL METAPLASIA OF THE GALLBLADDER, FOCAL. | |||
- CHRONIC CHOLECYSTITIS. | |||
- CHOLELITHIASIS. | |||
- NEGATIVE FOR DYSPLASIA. | |||
</pre> | |||
==See also== | |||
*[[Gallbladder]]. | |||
*[[Intestinal metaplasia]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Gallbladder]] | |||