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Difference between revisions of "Chromophobe renal cell carcinoma"
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Chromophobe renal cell carcinoma (view source)
Revision as of 14:32, 12 December 2013
, 14:32, 12 December 2013→IHC
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==IHC== | ==IHC== | ||
*CK7 +ve cell membrane.<ref name=Ref_GUP293>{{Ref GUP|293}}</ref> | *CK7 +ve cell membrane.<ref name=Ref_GUP293>{{Ref GUP|293}}</ref> | ||
**Useful for differentiating from oncocytoma. | |||
*CD117 +ve. | *CD117 +ve. | ||
*Vimentin -ve.<ref name=pmid22455881>{{Cite journal | last1 = Zhang | first1 = W. | last2 = Yu | first2 = WJ. | last3 = Jiang | first3 = YX. | last4 = Li | first4 = YJ. | last5 = Han | first5 = F. | last6 = Liu | first6 = Y. | last7 = Han | first7 = ZL. | title = [Chromophobe renal cell carcinoma: a clinicopathologic study and immunophenotypes of 42 cases]. | journal = Zhonghua Bing Li Xue Za Zhi | volume = 41 | issue = 2 | pages = 76-80 | month = Feb | year = 2012 | doi = | PMID = 22455881 }} | *Vimentin -ve.<ref name=pmid22455881>{{Cite journal | last1 = Zhang | first1 = W. | last2 = Yu | first2 = WJ. | last3 = Jiang | first3 = YX. | last4 = Li | first4 = YJ. | last5 = Han | first5 = F. | last6 = Liu | first6 = Y. | last7 = Han | first7 = ZL. | title = [Chromophobe renal cell carcinoma: a clinicopathologic study and immunophenotypes of 42 cases]. | journal = Zhonghua Bing Li Xue Za Zhi | volume = 41 | issue = 2 | pages = 76-80 | month = Feb | year = 2012 | doi = | PMID = 22455881 }} | ||
</ref> | </ref> | ||
ChRCC versus oncocytoma | Uncommon stains for ChRCC versus oncocytoma: | ||
*PAX2 -ve .<ref name=pmid17210525>{{cite journal |author=Memeo L, Jhang J, Assaad AM, ''et al.'' |title=Immunohistochemical analysis for cytokeratin 7, KIT, and PAX2: value in the differential diagnosis of chromophobe cell carcinoma |journal=Am. J. Clin. Pathol. |volume=127 |issue=2 |pages=225–9 |year=2007 |month=February |pmid=17210525 |doi=10.1309/9KWEA4W9Y94D1AEE |url=http://ajcp.ascpjournals.org/cgi/pmidlookup?view=long&pmid=17210525}}</ref> | *PAX2 -ve .<ref name=pmid17210525>{{cite journal |author=Memeo L, Jhang J, Assaad AM, ''et al.'' |title=Immunohistochemical analysis for cytokeratin 7, KIT, and PAX2: value in the differential diagnosis of chromophobe cell carcinoma |journal=Am. J. Clin. Pathol. |volume=127 |issue=2 |pages=225–9 |year=2007 |month=February |pmid=17210525 |doi=10.1309/9KWEA4W9Y94D1AEE |url=http://ajcp.ascpjournals.org/cgi/pmidlookup?view=long&pmid=17210525}}</ref> | ||
**ChRCC 10 of 11 -ve versus Oncocytoma 3 of 23 -ve. | **ChRCC 10 of 11 -ve versus Oncocytoma 3 of 23 -ve. | ||