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Difference between revisions of "Esophagus"
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→Squamous dysplasia of the esophagus
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===IHC=== | ===IHC=== | ||
*Ki-67 may be useful | *Ki-67 may be useful:<ref name=pmid21420715>{{Cite journal | last1 = Wang | first1 = WC. | last2 = Wu | first2 = TT. | last3 = Chandan | first3 = VS. | last4 = Lohse | first4 = CM. | last5 = Zhang | first5 = L. | title = Ki-67 and ProExC are useful immunohistochemical markers in esophageal squamous intraepithelial neoplasia. | journal = Hum Pathol | volume = 42 | issue = 10 | pages = 1430-7 | month = Oct | year = 2011 | doi = 10.1016/j.humpath.2010.12.009 | PMID = 21420715 }}</ref> | ||
**Reactive changes/normal ~98% negative. | |||
**Low-grade esophageal squamous intraepithelial neoplasia (LGESIN) ~80% intermediate, ~20% negative. | |||
**High-grade esophageal squamous intraepithelial neoplasia (HGESIN) ~40% intermediate, 60% strong. | |||
Definitions:<ref name=pmid21420715/> | |||
*Negative defined as: < 25% of epithelium +ve ''and'' staining only in lower quarter of epithelium. | |||
*Intermediate defined: >=25% and <=50% of epithelium +ve ''and'' only in the lower half of the epithelium. | |||
*Strong defined: >50% of epithelium +ve ''or'' upper half of epithelium. | |||
==Leiomyoma of the esophagus== | ==Leiomyoma of the esophagus== | ||