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Line 439: |
| ==Pigmented spindle cell nevus== | | ==Pigmented spindle cell nevus== |
| *[[AKA]] ''pigmented spindle cell nevus of Reed''. | | *[[AKA]] ''pigmented spindle cell nevus of Reed''. |
| | | {{Main|Pigmented spindle cell nevus}} |
| ===General===
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| *Uncommon.
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| *Women in teens & 20s.
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| *Location: shoulder, pelvic girdle region.
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| ===Microscopic===
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| Features:<ref name=Ref_WMSP500>{{Ref WMSP|500}}</ref>
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| *Nests of heavily pigmented spindle cells at dermal-epidermal junction - '''key feature'''.
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| **Nevoid cells in epidermis & dermis - form "basket weave" pattern
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| *Well-circumscribed lesion.
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| Notes:
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| *No epithelioid nevus cells.
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| DDx:
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| *[[Spitz nevus]].
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| *[[Malignant melanoma]].
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| ====Images====
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| <gallery>
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| Image:Pigmented_spindle_cell_nevus_-_low_mag.jpg | PSCN - low mag. (WC)
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| Image:Pigmented_spindle_cell_nevus_-_2_-_intermed_mag.jpg | PSCN - intermed. mag. (WC)
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| Image:Pigmented_spindle_cell_nevus_-_2_-_high_mag.jpg | PSCN - high mag. (WC)
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| </gallery>
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| www:
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| *[http://www.histopathology-india.net/Reed.htm Reed nevus - collection (histopathology-india.net)].
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| ===Sign out===
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| <pre>
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| SKIN LESION, RIGHT POSTERIOR NECK, EXCISION:
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| - PIGMENTED SPINDLE CELL NEVUS OF REED.
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| -- COMPLETELY EXCISED (CLEARANCE ~ 1 MM).
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| </pre>
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| | |
| ====Micro====
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| The sections show spindled pigmented melanocytes in nests confined to the epidermis.
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| The lesion is symmetrical in its architecture and pigment distribution. There is no
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| pagetoid spread of melanocytes in the epidermis. No significant nuclear atypia is
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| identified. No mitotic activity is appreciated. Melanophages are present in the superficial
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| dermis. The lesion is completely excised in the plane of section.
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|
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| ==Spitz nevus== | | ==Spitz nevus== |