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*Very rare<ref name=pmid16826585>{{Cite journal | last1 = Ashley | first1 = RA. | last2 = Inman | first2 = BA. | last3 = Sebo | first3 = TJ. | last4 = Leibovich | first4 = BC. | last5 = Blute | first5 = ML. | last6 = Kwon | first6 = ED. | last7 = Zincke | first7 = H. | title = Urachal carcinoma: clinicopathologic features and long-term outcomes of an aggressive malignancy. | journal = Cancer | volume = 107 | issue = 4 | pages = 712-20 | month = Aug | year = 2006 | doi = 10.1002/cncr.22060 | PMID = 16826585 }}</ref>~ 0.2% of bladder cancers.<ref name=pmid22901574>{{Cite journal | last1 = Bruins | first1 = HM. | last2 = Visser | first2 = O. | last3 = Ploeg | first3 = M. | last4 = Hulsbergen-van de Kaa | first4 = CA. | last5 = Kiemeney | first5 = LA. | last6 = Witjes | first6 = JA. | title = The clinical epidemiology of urachal carcinoma: results of a large, population based study. | journal = J Urol | volume = 188 | issue = 4 | pages = 1102-7 | month = Oct | year = 2012 | doi = 10.1016/j.juro.2012.06.020 | PMID = 22901574 }}</ref> | *Very rare<ref name=pmid16826585>{{Cite journal | last1 = Ashley | first1 = RA. | last2 = Inman | first2 = BA. | last3 = Sebo | first3 = TJ. | last4 = Leibovich | first4 = BC. | last5 = Blute | first5 = ML. | last6 = Kwon | first6 = ED. | last7 = Zincke | first7 = H. | title = Urachal carcinoma: clinicopathologic features and long-term outcomes of an aggressive malignancy. | journal = Cancer | volume = 107 | issue = 4 | pages = 712-20 | month = Aug | year = 2006 | doi = 10.1002/cncr.22060 | PMID = 16826585 }}</ref>~ 0.2% of bladder cancers.<ref name=pmid22901574>{{Cite journal | last1 = Bruins | first1 = HM. | last2 = Visser | first2 = O. | last3 = Ploeg | first3 = M. | last4 = Hulsbergen-van de Kaa | first4 = CA. | last5 = Kiemeney | first5 = LA. | last6 = Witjes | first6 = JA. | title = The clinical epidemiology of urachal carcinoma: results of a large, population based study. | journal = J Urol | volume = 188 | issue = 4 | pages = 1102-7 | month = Oct | year = 2012 | doi = 10.1016/j.juro.2012.06.020 | PMID = 22901574 }}</ref> | ||
*Younger <55 years-old. | *Younger <55 years-old. | ||
Treatment: | |||
*Partial cystectomy +/- umbilectomy. | |||
===Gross=== | ===Gross=== | ||
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*Adjacent urothelium typically benign. | *Adjacent urothelium typically benign. | ||
DDx:<ref>{{Ref Amin|2-143}}</ref> | DDx:<ref name=Ref_Amin2-143>{{Ref Amin|2-143}}</ref> | ||
*[[Adenocarcinoma of the urinary bladder]]. | *[[Adenocarcinoma of the urinary bladder]]. | ||
*Invasive [[urothelial carcinoma]] with glandular differentiation. | *Invasive [[urothelial carcinoma]] with glandular differentiation. | ||
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*CK34betaE12 +ve in UC (-ve in CRC). | *CK34betaE12 +ve in UC (-ve in CRC). | ||
*Beta-catenin -ve nuclei in UC (+ve nuclei in CRC). | *Beta-catenin -ve nuclei in UC (+ve nuclei in CRC). | ||
===Sign out=== | |||
*The diagnosis is clinicopathologic; one needs imaging.<ref name=Ref_Amin2-143>{{Ref Amin|2-143}}</ref> | |||
==Urinary bladder infarct== | ==Urinary bladder infarct== |
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