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Carcinoma ex pleomorphic adenoma (view source)
Revision as of 16:10, 2 December 2013
, 16:10, 2 December 2013+SO
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*CK7 +ve. | *CK7 +ve. | ||
*AE1/AE3 +ve. | *AE1/AE3 +ve. | ||
==Sign out== | |||
<pre> | |||
PAROTID GLAND (MASS), LEFT, EXCISION: | |||
- CARCINOMA EX PLEOMORPHIC ADENOMA, LOW-GRADE, INTRACAPSULAR. | |||
-- MARGINS NEGATIVE. | |||
-- SEE TUMOUR SUMMARY AND COMMENTS. | |||
- THREE BENIGN LYMPH NODES. | |||
</pre> | |||
===Micro=== | |||
The sections show a lesion with spindled (myoepithelial) cells and an epithelial component, | |||
on a background of a chondromyxoid stroma. The lesion is encapsulated by a thin layer of | |||
fibrous tissue. | |||
Focally, within the lesion, nuclear atypia and mitotic activity are identified, including an atypical mitotic figure. The atypical region stains with p53. Approximately 45% of the atypical cells stain with Ki-67. There is no appreciable HER2 staining. | |||
Unremarkable parotid gland and lymph nodes are present. | |||
==See also== | ==See also== | ||