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Difference between revisions of "Rosai-Dorfman disease"
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| Width = | | Width = | ||
| Caption = Rosai-Dorfman disease. H&E stain. | | Caption = Rosai-Dorfman disease. H&E stain. | ||
| Micro = | | Micro = sinus histiocytosis - histiocytes have a singular large round nucleus with a prominent nucleolus (visible with 10x objective); emperipolesis | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = | | LMDDx = | ||
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DDx: | DDx: | ||
*[[Sinus histiocytosis]]. | |||
*Other histiocytosis: | *Other histiocytosis: | ||
**[[Langerhans cell histiocytosis]]. | **[[Langerhans cell histiocytosis]]. | ||
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Image:Emperipolesis_-_very_high_mag.jpg | Emperipolesis in SHML (WC) | Image:Emperipolesis_-_very_high_mag.jpg | Emperipolesis in SHML (WC) | ||
Image:Rosai-Dorfman_disease_-_very_high_mag.jpg | Rosai-Dorfman disease (WC) | Image:Rosai-Dorfman_disease_-_very_high_mag.jpg | Rosai-Dorfman disease (WC) | ||
Image:Rosai-dorfman.jpg | Rosai-Dorfman disease - | Image:Rosai-dorfman.jpg | Rosai-Dorfman disease - S-100 showing emperipolesis (WC) | ||
</gallery> | </gallery> | ||
www: | www: | ||
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==IHC== | ==IHC== | ||
*CD68 +ve. | *CD68 +ve. | ||
* | *S-100 +ve. | ||
**Useful for seeing emperipolesis. | **Useful for seeing emperipolesis. | ||
*CD1a -ve. | *CD1a -ve. | ||
**CD1a | **CD1a +ve in [[Langerhans cell histiocytosis]]. | ||
==See also== | ==See also== | ||