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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Micro = cyst lining by a stratified squamous epithelium with a granular layer - contains keratin, +/-[[granuloma|Granulomatous inflammation]] due to rupture, no significant nuclear atypia | |||
| Subtypes = | |||
| LMDDx = [[pilar cyst]], [[eccrine hidrocystoma]] (eyelid), [[dermoid cyst]], cystic [[squamous cell carcinoma of the skin|squamous cell carcinoma]], [[keratoacanthoma]], [[dermatofibrosarcoma protuberans]], hybrid epidermoid and trichilemmal cyst | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = nodule +/-yellow colour | |||
| Grossing = | |||
| Site = [[skin]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = very common | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = other [[skin cysts]] | |||
}} | |||
'''Epidermal inclusion cyst''', abbreviated '''EIC''', is a very common [[skin]] pathology. It is also know as '''epidermal cyst''', '''epidermoid cyst''',<ref name=Ref_Derm302>{{Ref Derm|302}}</ref> and '''follicular cyst, infundibular type'''. | '''Epidermal inclusion cyst''', abbreviated '''EIC''', is a very common [[skin]] pathology. It is also know as '''epidermal cyst''', '''epidermoid cyst''',<ref name=Ref_Derm302>{{Ref Derm|302}}</ref> and '''follicular cyst, infundibular type'''. | ||
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Cyst lining | *Cyst lining by a stratified squamous epithelium with a granular layer - '''key feature'''.<ref>URL: [http://emedicine.medscape.com/article/1058907-diagnosis http://emedicine.medscape.com/article/1058907-diagnosis]. Accessed on: 18 March 2011.</ref> | ||
* | **No significant nuclear atypia. | ||
* | **Contains keratin - acellular, lamellar appearance. | ||
*+/-[[granuloma|Granulomatous inflammation]] due to rupture. | *+/-[[granuloma|Granulomatous inflammation]] due to rupture. | ||
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