Difference between revisions of "Salivary glands"

Salivary glands (view source)

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 ==Carcinoma ex pleomorphic adenoma==
 *Abbreviated ''Ca ex PA''.
+{{Main|Carcinoma ex pleomorphic adenoma}}
-===General===
-Definition:
-*Malignant transformation of a ''[[pleomorphic adenoma]]''.
-Diagnosis (either 1 or 2):
-#History of a pleomorphic adenoma at the same site.
-#Features of a pleomorphic adenoma and a carcinoma.
-Epidemiology:
-*Rare.
-===Microscopic===
-Features:
-*Cells with cytologic features of malignancy.
-*Architecture (any of the following):
-**Glands.
-**Nests.
-**Single cells (may be subtle).
-Architectural patterns:
-*Ductal carcinoma NOS (arising from ductal cells) - most common pattern for Ca ex PA.
-*Myoepithelial cacinoma NOS (arising from myoepithelial cells).
-*"Named carcinoma":
-**Salivary duct carcinoma - second most common pattern for Ca ex PA.
-**Mucoepidermoid carcinoma.
-**Adenoid cystic carcinoma.
-Note:
-*Often adenocarcinoma-like.
-*Myoepithelial cells may be clear cells. (???)
-====Subclassification====
-Extent of invasion:<ref>URL: [http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/MajorSalGlands_11protocol.pdf http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/MajorSalGlands_11protocol.pdf]. Accessed on: 2 April 2012.</ref>
-#Non-invasive [[AKA]] ''intracapsular'' [[AKA]] ''in situ''.
-#Minimally invasive <=1.5 mm beyond the capsule.
-#Widely invasive >1.5 mm beyond the capsule.
 ==Epithelial-myoepithelial carcinoma==