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+images, micro for sertoli cell tumour
m (→Choriocarcinoma: copyedit) |
(+images, micro for sertoli cell tumour) |
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**AKA ''MART-1''. | **AKA ''MART-1''. | ||
**Expressed in melanoma, adrenal tissue, steroid-secreting tumours. | **Expressed in melanoma, adrenal tissue, steroid-secreting tumours. | ||
==Sertoli cell tumour== | |||
*Arises from ''Sertoli cells'' ([[AKA]] nurse cells). | |||
===Microscopic=== | |||
Features: | |||
*Groups of cells in ''chords'' or ''trabeculae'' (beam-like arrangement). | |||
*Cells have: | |||
**Light staining bubbly cytoplasm +/- large cytoplasmic vacuoles. | |||
**Slightly irregular nucleoli. | |||
**Granular irregular appearing chromatin. | |||
Negatives: | |||
*Mitoses are rare. | |||
*No significant nuclear atypia. | |||
Image(s): | |||
*[http://commons.wikimedia.org/wiki/File:Sertoli_cell_tumour_high_mag.jpg Sertoli cell tumour - high mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Sertoli_cell_tumour_low_mag.jpg Sertoli cell tumour - low mag. (WC)]. | |||
==See also== | ==See also== | ||