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Difference between revisions of "Papillary renal cell carcinoma"
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Papillary renal cell carcinoma (view source)
Revision as of 02:47, 15 November 2013
, 02:47, 15 November 2013→Histological subtyping
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===Histological subtyping=== | ===Histological subtyping=== | ||
Subtypes:<ref name=Ref_GUP289>{{Ref GUP|289}}</ref> | Subtypes:<ref name=Ref_GUP289>{{Ref GUP|289}}</ref><ref>{{Cite journal | last1 = Delahunt | first1 = B. | last2 = Eble | first2 = JN. | title = Papillary renal cell carcinoma: a clinicopathologic and immunohistochemical study of 105 tumors. | journal = Mod Pathol | volume = 10 | issue = 6 | pages = 537-44 | month = Jun | year = 1997 | doi = | PMID = 9195569 }}</ref> | ||
*''Type 1'' - single layer of cells on basement membrane. | *''Type 1'' - single layer of cells on basement membrane - '''most important'''. | ||
** | ** Usually low grade nuclear features, i.e. low Fuhrman grade. | ||
*''Type 2'' - pseudostratification of cells. | ** Other characteristics: | ||
*** Clear cytoplasm. | |||
*** Foamy macrophages - common. | |||
*''Type 2'' - pseudostratification of cells - '''most important'''. | |||
** Usually high grade nuclear features, i.e. high Fuhrman grade. | ** Usually high grade nuclear features, i.e. high Fuhrman grade. | ||
** Other characteristics: | |||
*** Eosinophilic cytoplasm. | |||
*** Foamy macrophages - uncommon. | |||
Another subtype: | |||
*''Oncocytic'' - oncocytic cytoplasm. | *''Oncocytic'' - oncocytic cytoplasm. | ||
**Extremely rare ~ largest series is 12 cases.<ref name=pmid19494850 >{{Cite journal | last1 = Srigley | first1 = JR. | last2 = Delahunt | first2 = B. | title = Uncommon and recently described renal carcinomas. | journal = Mod Pathol | volume = 22 Suppl 2 | issue = | pages = S2-S23 | month = Jun | year = 2009 | doi = 10.1038/modpathol.2009.70 | PMID = 19494850 }}</ref> | **Extremely rare ~ largest series is 12 cases.<ref name=pmid19494850 >{{Cite journal | last1 = Srigley | first1 = JR. | last2 = Delahunt | first2 = B. | title = Uncommon and recently described renal carcinomas. | journal = Mod Pathol | volume = 22 Suppl 2 | issue = | pages = S2-S23 | month = Jun | year = 2009 | doi = 10.1038/modpathol.2009.70 | PMID = 19494850 }}</ref> | ||