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Difference between revisions of "Craniopharyngioma"
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'''Craniopharyngioma''' is a benign [[neuropathology tumour]]. | |||
==General== | |||
*Develop from remains of Rathke's pouch or squamous epithelial cell rests.<ref name=pmid17425791>{{Cite journal | last1 = Garnett | first1 = MR. | last2 = Puget | first2 = S. | last3 = Grill | first3 = J. | last4 = Sainte-Rose | first4 = C. | title = Craniopharyngioma. | journal = Orphanet J Rare Dis | volume = 2 | issue = | pages = 18 | month = | year = 2007 | doi = 10.1186/1750-1172-2-18 | PMID = 17425791 }}</ref> | |||
Comes in two flavours:<ref name=pmid17425791/> | |||
*Adamantinomatous type. | |||
**Adults and children. | |||
*Squamous papillary type. | |||
**Adults individuals.<ref name=pmid6696166>{{Cite journal | last1 = Giangaspero | first1 = F. | last2 = Burger | first2 = PC. | last3 = Osborne | first3 = DR. | last4 = Stein | first4 = RB. | title = Suprasellar papillary squamous epithelioma ("papillary craniopharyngioma"). | journal = Am J Surg Pathol | volume = 8 | issue = 1 | pages = 57-64 | month = Jan | year = 1984 | doi = | PMID = 6696166 }}</ref> | |||
**Usually solid. | |||
Radiology:<ref name=pmid17425791/> | |||
*Calcified - adamantinomatous type only. | |||
*Solid & cystic. | |||
==Microscopic== | |||
===Adamantinomatous=== | |||
Features (adamantinomatous):<ref name=Ref_DCHH184>{{Ref DCHH|184}}</ref> | |||
*Well-circumscribed (or pseudoinvasive border). | |||
*Multicystic. | |||
*Small-to-medium sized cells with moderate amount of basophilic cytoplasm. | |||
*Bland nuclei (with occ. small nucleoli). | |||
*"Wet" keratin - nests of whorled keratin. | |||
*Calcifications (non-psammomatous). | |||
====Images==== | |||
<gallery> | |||
Image:Adamantinomatous_craniopharyngioma_-_very_low_mag.jpg | Adamantinomatous craniopharyngioma - very low mag. (WC/Nephron) | |||
Image:Adamantinomatous_craniopharyngioma_-_intermed_mag.jpg | Adamantinomatous craniopharyngioma - intermed. mag. (WC/Nephron) | |||
Image:Adamantinomatous_craniopharyngioma_-_very_high_mag.jpg | Adamantinomatous craniopharyngioma - very high mag. (WC/Nephron) | |||
</gallery> | |||
===Papillary=== | |||
Features (papillary):<ref name=Ref_PSNP406>{{Ref PSNP|406}}</ref> | |||
*Non-keratinized squamous epithelium (without nuclear atypia). | |||
*Fibrovascular cores (required for ''papillary''). | |||
Notes: | |||
*+/-Cilia (rare). | |||
*+/-Goblet cell-like formations (rare). | |||
====Image==== | |||
<gallery> | |||
Image:Papillary_craniopharyngioma_-_intermed_mag.jpg |Papillary craniopharyngioma - intermed. mag. (WC/Nephron) | |||
Image:Papillary_craniopharyngioma_-_very_high_mag.jpg |Papillary craniopharyngioma - very high mag. (WC/Nephron) | |||
</gallery> | |||
www: | |||
*[http://library.med.utah.edu/WebPath/jpeg4/ENDO115.jpg Craniopharyngioma (med.utah.edu)].<ref>URL: [http://library.med.utah.edu/WebPath/jpeg4/ENDO115.jpg http://library.med.utah.edu/WebPath/jpeg4/ENDO115.jpg]. Accessed on: 6 December 2010.</ref> | |||
==See also== | |||
*[[Pituitary gland]]. | |||
*[[Neuropathology tumours]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Neuropathology]] | |||