|
|
Line 576: |
Line 576: |
|
| |
|
| ==Endometrial changes of oral contraception== | | ==Endometrial changes of oral contraception== |
| {{ Infobox external links
| | {{Main|Endometrium with hormonal changes}} |
| | Name = Endometrial changes of oral contraception
| |
| | EHVSC = 10170
| |
| | pathprotocols =
| |
| | wikipedia =
| |
| | pathoutlines =
| |
| }}
| |
| {{Main|Oral contraceptive pill}} | |
| :''Endometrium with hormonal changes'' and ''OCP endometrium'' redirect here.
| |
| *[[AKA]] ''oral contraceptive effect''.
| |
| ===General===
| |
| *Very common.
| |
| *Most pills a mix of progesterone and estrogen.
| |
| **The progesterone is what generates the characteristic appearance -- that is similar to pregnancy.
| |
| | |
| ===Microscopic===
| |
| Features:<ref name=Ref_PBoD1082>{{Ref PBoD|1082}}</ref>
| |
| *Inactive glands (round/ovoid glands, simple cuboidal epithelium, no mitoses).
| |
| *Stroma decidualized -- mnemonic ''NEW'':
| |
| **Nucleus central.
| |
| **Eosinophilic cytoplasm.
| |
| **Well-defined cell borders.
| |
| | |
| DDx:
| |
| *[[Endometrial hyperplasia with secretory changes]] - proliferative activity.
| |
| *[[Secretory phase endometrium]] - glandular changes of the secretory phase (cytoplasmic vacuolization), secretions in the glands.
| |
| | |
| ====Image====
| |
| <gallery>
| |
| Image:Endometrium_ocp_use3.jpg | Endometrium of woman on an OCP. (WC/Nephron)
| |
| </gallery>
| |
| ===Sign out===
| |
| <pre>
| |
| ENDOMETRIUM, BIOPSY:
| |
| - NON-PROLIFERATIVE ENDOMETRIAL GLANDS WITH STROMAL DECIDUALIZATION, CONSISTENT
| |
| WITH EXOGENOUS HORMONES.
| |
| </pre>
| |
| | |
| ====OCP effect and shedding endometrium====
| |
| <pre>
| |
| ENDOMETRIUM, ASPIRATION:
| |
| - ENDOMETRIUM WITH NONPROLIFERATIVE ENDOMETRIAL GLANDS AND
| |
| STROMAL DECIDUALIZATION, COMPATIBLE WITH EXOGENOUS HORMONES.
| |
| - EVIDENCE OF ENDOMETRIAL SHEDDING (BALLS OF CONDENSED STROMA
| |
| ASSOCIATED NEUTROPHILS, AND BLOOD).
| |
| - NEGATIVE FOR HYPERPLASIA AND NEGATIVE FOR MALIGNANCY.
| |
| </pre>
| |
|
| |
|
| ==Atrophic endometrium== | | ==Atrophic endometrium== |