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Endometrium with changes due to exogenous hormones (view source)
Revision as of 14:47, 27 November 2015
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Endometrium with hormone effect -- high mag.jpg | |||
| Width = | |||
| Caption = Endometrium with changes due to exogenous hormones. [[H&E stain]]. | |||
| Micro = inactive glands (round/ovoid glands, simple cuboidal epithelium, no mitoses), decidualized stroma (nucleus central, eosinophilic cytoplasm, well-defined cell borders) | |||
| Subtypes = | |||
| LMDDx = [[endometrial hyperplasia with secretory changes]], [[secretory phase endometrium]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[endometrium]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = exogenous hormones ([[oral contraceptive pill]] or hormone releasing intrauterine device) | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
}} | |||
{{ Infobox external links | {{ Infobox external links | ||
| Name = | | Name = {{PAGENAME}} | ||
| EHVSC = 10170 | | EHVSC = 10170 | ||
| pathprotocols = | | pathprotocols = | ||
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| pathoutlines = | | pathoutlines = | ||
}} | }} | ||
'''Endometrium with | '''Endometrium with changes due to exogenous hormones''' is relatively common in [[endometrium|endometrial]] samples. | ||
'''Endometrial changes of oral contraception''', '''oral contraceptive effect''' and ''' | '''Endometrial changes of oral contraception''', '''oral contraceptive effect''', '''OCP endometrium''', and '''endometrium with hormonal changes''' redirect here. | ||
The oral contraceptive pill is dealt with in the article ''[[oral contraceptive pill]]''. | The oral contraceptive pill is dealt with in the article ''[[oral contraceptive pill]]''. | ||
==General== | ==General== | ||
*Very common. | *Very common. | ||
*Most pills a mix of progesterone and estrogen. | *Most pills are a mix of progesterone and estrogen. | ||
**The progesterone is what generates the characteristic appearance -- that is similar to pregnancy. | **The progesterone is what generates the characteristic appearance -- that is similar to [[pregnancy]]. | ||
*Same appearance is seen with a levonorgestrel-releasing intrauterine device, e.g. ''Mirena''. | |||
==Microscopic== | ==Microscopic== | ||
| Line 30: | Line 60: | ||
===Image=== | ===Image=== | ||
<gallery> | <gallery> | ||
Image:Endometrium_ocp_use1.jpg | Endometrium of woman on an OCP. (WC/Nephron) | |||
Image:Endometrium_ocp_use2.jpg | Endometrium of woman on an OCP. (WC/Nephron) | |||
Image:Endometrium_ocp_use3.jpg | Endometrium of woman on an OCP. (WC/Nephron) | Image:Endometrium_ocp_use3.jpg | Endometrium of woman on an OCP. (WC/Nephron) | ||
</gallery> | |||
<gallery> | |||
Image: Endometrium with hormone effect -- intermed mag.jpg | Hormone effect - intermed. mag. (WC) | |||
Image: Endometrium with hormone effect -- high mag.jpg | Hormone effect - high mag. (WC) | |||
Image: Endometrium with hormone effect -- very high mag.jpg | Hormone effect - very high mag. (WC) | |||
</gallery> | </gallery> | ||
==Sign out== | ==Sign out== | ||
<pre> | |||
Endometrium, Curettage: | |||
- Endometrium with nonproliferative endometrial glands and stromal decidualization, | |||
consistent with exogenous hormones. | |||
</pre> | |||
====Block letters==== | |||
<pre> | <pre> | ||
ENDOMETRIUM, BIOPSY: | ENDOMETRIUM, BIOPSY: | ||
| Line 48: | Line 92: | ||
- NEGATIVE FOR HYPERPLASIA AND NEGATIVE FOR MALIGNANCY. | - NEGATIVE FOR HYPERPLASIA AND NEGATIVE FOR MALIGNANCY. | ||
</pre> | </pre> | ||
===Micro=== | |||
The sections show endometrium with nonproliferative endometrial glands and stromal | |||
decidualization. The gland-to-stroma ratio is within normal limits. | |||
==See also== | ==See also== | ||
*[[Endometrium]]. | *[[Endometrium]]. | ||
*[[Endometrial hyperplasia with secretory changes]]. | *[[Endometrial hyperplasia with secretory changes]]. | ||
*[[Decidualized endometrium]]. | |||
==References== | ==References== | ||