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Difference between revisions of "Colorectal tumours"
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*[http://jcp.bmjjournals.com/content/62/8/679/F3.large.jpg TILs in endometrial carcinoma (bmjjournals.com)].<ref name=pmid19638537>{{Cite journal | last1 = Garg | first1 = K. | last2 = Soslow | first2 = RA. | title = Lynch syndrome (hereditary non-polyposis colorectal cancer) and endometrial carcinoma. | journal = J Clin Pathol | volume = 62 | issue = 8 | pages = 679-84 | month = Aug | year = 2009 | doi = 10.1136/jcp.2009.064949 | PMID = 19638537 | URL = http://jcp.bmjjournals.com/content/62/8/679.full?related-urls=yes&legid=jclinpath;62/8/679 }}</ref> | *[http://jcp.bmjjournals.com/content/62/8/679/F3.large.jpg TILs in endometrial carcinoma (bmjjournals.com)].<ref name=pmid19638537>{{Cite journal | last1 = Garg | first1 = K. | last2 = Soslow | first2 = RA. | title = Lynch syndrome (hereditary non-polyposis colorectal cancer) and endometrial carcinoma. | journal = J Clin Pathol | volume = 62 | issue = 8 | pages = 679-84 | month = Aug | year = 2009 | doi = 10.1136/jcp.2009.064949 | PMID = 19638537 | URL = http://jcp.bmjjournals.com/content/62/8/679.full?related-urls=yes&legid=jclinpath;62/8/679 }}</ref> | ||
*[http://ajcp.ascpjournals.org/content/134/3/478/F2.expansion.html TILs in CRC (ascpjournals.org)].<ref name=pmid20716806/> | *[http://ajcp.ascpjournals.org/content/134/3/478/F2.expansion.html TILs in CRC (ascpjournals.org)].<ref name=pmid20716806/> | ||
====Tumour regression==== | |||
There is a three tiered regression grading system by Ryan ''et al''. for [[colorectal cancer]]:<ref name=pmid16045774>{{Cite journal | last1 = Ryan | first1 = R. | last2 = Gibbons | first2 = D. | last3 = Hyland | first3 = JM. | last4 = Treanor | first4 = D. | last5 = White | first5 = A. | last6 = Mulcahy | first6 = HE. | last7 = O'Donoghue | first7 = DP. | last8 = Moriarty | first8 = M. | last9 = Fennelly | first9 = D. | title = Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer. | journal = Histopathology | volume = 47 | issue = 2 | pages = 141-6 | month = Aug | year = 2005 | doi = 10.1111/j.1365-2559.2005.02176.x | PMID = 16045774 }}</ref> | |||
{| class="wikitable sortable" | |||
! Grade | |||
! Features | |||
|- | |||
| Grade 1 | |||
| small groups of tumour cells or single tumour cells | |||
|- | |||
| Grade 2 | |||
| definite tumour but more fibrosis ("cancer outgrown by fibrosis") | |||
|- | |||
| Grade 3 | |||
| definite tumour with no fibrosis ''or'' tumour with a lesser amount of fibrosis ("fibrosis outgrown by cancer") | |||
|} | |||
===IHC=== | ===IHC=== | ||