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#**Normal spacing is ~1x smallest villus or larger. | #**Normal spacing is ~1x smallest villus or larger. | ||
#***In perivillous fibrin deposition - spacing usu. larger than normal. | #***In perivillous fibrin deposition - spacing usu. larger than normal. | ||
#Prominent syncytial knots. | #Prominent syncytial knots. ‡ | ||
#Thickened trophoblastic basement membrane (below [[cytotrophoblast]]s). | #Thickened trophoblastic basement membrane (below [[cytotrophoblast]]s). | ||
#+/-Changes seen in decidual vasculopathy: | #+/-Changes seen in decidual vasculopathy: | ||
Line 851: | Line 851: | ||
#**[[Fibrinoid necrosis]]. | #**[[Fibrinoid necrosis]]. | ||
#**Vessel wall lipid deposition. | #**Vessel wall lipid deposition. | ||
Note: | |||
*‡ The normal number is dependent on the gestational age:<ref name=pmid20017638>{{Cite journal | last1 = Loukeris | first1 = K. | last2 = Sela | first2 = R. | last3 = Baergen | first3 = RN. | title = Syncytial knots as a reflection of placental maturity: reference values for 20 to 40 weeks' gestational age. | journal = Pediatr Dev Pathol | volume = 13 | issue = 4 | pages = 305-9 | month = | year = | doi = 10.2350/09-08-0692-OA.1 | PMID = 20017638 }}</ref> | |||
<center> | |||
{| class="wikitable sortable" | |||
! Gestational age | |||
! Villi with knots (average) | |||
! Villi with knots (range) | |||
|- | |||
| 40 weeks | |||
| 29 % | |||
| 27-36 % | |||
|- | |||
| 39 weeks | |||
| 29 % | |||
| 23-34% | |||
|- | |||
| 38 weeks | |||
| 27 % | |||
| 23-33 % | |||
|- | |||
| 37 weeks | |||
| 28 % | |||
| 24-33 % | |||
|- | |||
| 36 weeks | |||
| 23 % | |||
| 20-26 | |||
|- | |||
| 34 weeks | |||
| 18 % | |||
| 12-22 % | |||
|- | |||
| 32 weeks | |||
| 13 % | |||
| 10-16 % | |||
|- | |||
| 30 weeks | |||
| 13 % | |||
| 10-17 % | |||
|- | |||
| 26 weeks | |||
| 11 % | |||
| 10-13 % | |||
|- | |||
| 22 weeks | |||
| 7 % | |||
| 5-9 % | |||
|} | |||
</center> | |||
====Images==== | ====Images==== |
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