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Difference between revisions of "Basal cell carcinoma"
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| LMDDx = [[trichoepithelioma]], [[adenoid cystic carcinoma]], [[eccrine poroma]], reticulated [[seborrheic keratosis]] (for BCC, fibroepitheliomatous pattern), [[basaloid squamous cell carcinoma]], [[basosquamous carcinoma]] | | LMDDx = [[trichoepithelioma]], [[adenoid cystic carcinoma]], [[eccrine poroma]], reticulated [[seborrheic keratosis]] (for BCC, fibroepitheliomatous pattern), [[basaloid squamous cell carcinoma]], [[basosquamous carcinoma]] | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = Ber-EP4 +ve, EMA -ve | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
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*[[Basosquamous carcinoma]] - squamous cell carcinoma with basal cell carcinoma (a collision tumour). | *[[Basosquamous carcinoma]] - squamous cell carcinoma with basal cell carcinoma (a collision tumour). | ||
*[[Solar elastosis]] with ectatic [[blood vessel]]s. | *[[Solar elastosis]] with ectatic [[blood vessel]]s. | ||
*[[Microcystic adnexal carcinoma]] - for sclerosing basal cell carcinoma. | |||
===Images=== | ===Images=== | ||
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==IHC== | ==IHC== | ||
*Ber-EP4 +ve. | |||
**[[Microcystic adnexal carcinoma]] negative.<ref name=pmid23398472 >{{Cite journal | last1 = Sellheyer | first1 = K. | last2 = Nelson | first2 = P. | last3 = Kutzner | first3 = H. | last4 = Patel | first4 = RM. | title = The immunohistochemical differential diagnosis of microcystic adnexal carcinoma, desmoplastic trichoepithelioma and morpheaform basal cell carcinoma using BerEP4 and stem cell markers. | journal = J Cutan Pathol | volume = 40 | issue = 4 | pages = 363-70 | month = Apr | year = 2013 | doi = 10.1111/cup.12085 | PMID = 23398472 }}</ref> | |||
*CK5/6 +ve. | *CK5/6 +ve. | ||
**Useful to assess [[margins]]... if very close. | **Useful to assess [[margins]]... if very close. | ||