Difference between revisions of "Non-malignant skin disease"

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Non-malignant skin disease (view source)

Revision as of 01:50, 14 October 2013

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→‎Fibroepithelial polyp: split-out
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==Fibroepithelial polyp==
==Fibroepithelial polyp==
*[[AKA]] ''acrochordon''.
{{Main|Fibroepithelial polyp}}
*[[AKA]] ''skin tag''.
===General===
*Benign.
*Older people.
*May be associated with pregnancy, [[diabetes]], [[intestinal polyposis]].<ref name=Ref_PCPBoD8|596>{{Ref PCPBoD8|596}}</ref>
*Can be a component of ''[[Birt–Hogg–Dubé syndrome]]''.
 
===Gross===
*Raised skin-coloured lesion.
 
Image:
*[http://commons.wikimedia.org/wiki/File:Skintagblemish.jpg Skin tag (WC)].
 
===Microscopic===
Features:
*On a stalk / epithelium on three sides.
*Benign epidermis.
 
DDx:
*Pedunculated [[seborrheic keratosis]] - typically have epidermal hyperplasia, hyperkeratosis, horn cysts.<ref name=Ref_Derm342>{{Ref Derm|342}}</ref>
*Regressing [[melanocytic lesions]].
**[[Intradermal melanocytic nevus]].
*[[Nevus lipomatosus superficialis]] - abundant adipocytes in the superficial dermis.
*[[Neurofibroma]].
 
====Images====
<gallery>
Image:SkinTumors-P9250819.jpg | Skin tag. (WC)
</gallery>
www:
*[http://dermatlas.med.jhmi.edu/derm/IndexDisplay.cfm?ImageID=1767547949 Fibroepithelial polyp (dermatlas.med.jhmi.edu)].<ref>URL: [http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=1196583692 http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=1196583692]. Accessed on: 1 September 2011.</ref>
*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20080802171929218 Fibroepithelial polyp (surgicalpathologyatlas.com)].
*[http://dermatology-s10.cdlib.org/143/case_presentations/skintags/3.jpg Inflamed fibroepithelial polyp (cdlib.org)].<ref>URL: [http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html]. Accessed on: 9 January 2013.</ref>
===Sign out===
<pre>
EYELID ("TAG"), RIGHT, REMOVAL:
- BENIGN FIBROEPITHELIAL POLYP.
</pre>
<pre>
SKIN ("SKIN TAG"), THIGH, REMOVAL:
- FIBROEPITHELIAL POLYP.
</pre>
 
====Micro====
The sections show a fragment of skin with epithelium on three sides.  The epithelium matures normally and is not hypertrophic.  Orthokeratosis is present. The core of the lesion has fibrous tissue.  There is no significant inflammation. No melanocytic nests are identified.
 
=====Inflamed=====
The sections show a fragment of skin with epithelium on three sides. The epithelium matures
and is acanthotic. Minimal parakeratosis is present. The core of the lesion consists of
fibrous tissue with a mild lymphocyte-predominant dermal infiltrate.  Rare siderophages are
present.
 
There is mild basal nuclear enlargement.  No significant nuclear atypia is apparent. The
dermal-epidermal interface is well-demarcated. Rare basal mitotic activity is identified.


==Actinic keratosis==
==Actinic keratosis==
Michael
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