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Difference between revisions of "Immunohistochemical staining"
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Immunohistochemical staining (view source)
Revision as of 20:11, 9 October 2013
, 20:11, 9 October 2013→Vimentin & cytokeratin
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Mnemonic: ''NASH TURP''. | Mnemonic: ''NASH TURP''. | ||
==Vimentin | ==Vimentin and cytokeratin positivity== | ||
A few tumours are positive for both vimentin and cytokeratins. | A few tumours are positive for both vimentin and cytokeratins. | ||
Common tumours: | Common tumours: | ||
*[[Renal cell carcinoma]]. | *[[Renal cell carcinoma]].<ref name=pmid18318577/> | ||
*[[Endometrial carcinoma]].<ref name=pmid12647218/> | *[[Endometrial carcinoma]].<ref name=pmid12647218/> | ||
*[[Ovarian serous carcinoma]].<ref name=pmid18318577>{{Cite journal | last1 = Bahrami | first1 = A. | last2 = Truong | first2 = LD. | last3 = Ro | first3 = JY. | title = Undifferentiated tumor: true identity by immunohistochemistry. | journal = Arch Pathol Lab Med | volume = 132 | issue = 3 | pages = 326-48 | month = Mar | year = 2008 | doi = 10.1043/1543-2165(2008)132[326:UTTIBI]2.0.CO;2 | PMID = 18318577 }}</ref> | |||
*[[Papillary thyroid carcinoma]].<ref name=pmid18318577/> | |||
*[[ | *[[Sarcomatoid carcinoma]] (spindle cell carcinoma).<ref name=pmid18318577/> | ||
Rare tumours: | Rare tumours: | ||
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*[[Rhabdoid tumour]].<ref name=pmid11557780>{{cite journal |author=Itakura E, Tamiya S, Morita K, ''et al.'' |title=Subcellular distribution of cytokeratin and vimentin in malignant rhabdoid tumor: three-dimensional imaging with confocal laser scanning microscopy and double immunofluorescence |journal=Mod. Pathol. |volume=14 |issue=9 |pages=854–61 |year=2001 |month=September |pmid=11557780 |doi=10.1038/modpathol.3880401 |url=http://www.nature.com/modpathol/journal/v14/n9/full/3880401a.html}}</ref> | *[[Rhabdoid tumour]].<ref name=pmid11557780>{{cite journal |author=Itakura E, Tamiya S, Morita K, ''et al.'' |title=Subcellular distribution of cytokeratin and vimentin in malignant rhabdoid tumor: three-dimensional imaging with confocal laser scanning microscopy and double immunofluorescence |journal=Mod. Pathol. |volume=14 |issue=9 |pages=854–61 |year=2001 |month=September |pmid=11557780 |doi=10.1038/modpathol.3880401 |url=http://www.nature.com/modpathol/journal/v14/n9/full/3880401a.html}}</ref> | ||
*[[Epithelioid sarcoma]].<ref name=pmid10452506>{{cite journal |author=Miettinen M, Fanburg-Smith JC, Virolainen M, Shmookler BM, Fetsch JF |title=Epithelioid sarcoma: an immunohistochemical analysis of 112 classical and variant cases and a discussion of the differential diagnosis |journal=Hum. Pathol. |volume=30 |issue=8 |pages=934–42 |year=1999 |month=August |pmid=10452506 |doi= |url=}}</ref> | *[[Epithelioid sarcoma]].<ref name=pmid10452506>{{cite journal |author=Miettinen M, Fanburg-Smith JC, Virolainen M, Shmookler BM, Fetsch JF |title=Epithelioid sarcoma: an immunohistochemical analysis of 112 classical and variant cases and a discussion of the differential diagnosis |journal=Hum. Pathol. |volume=30 |issue=8 |pages=934–42 |year=1999 |month=August |pmid=10452506 |doi= |url=}}</ref> | ||
*[[Epithelioid angiosarcoma]].<ref name=pmid18318577/> | |||
*[[Desmoplastic small round cell tumour]].<ref name=pmid18318577/> | |||
*[[Anaplastic thyroid carcinoma]].<ref name=pmid18318577/> | |||
*Biphasic [[malignant mesothelioma]].<ref name=pmid18318577/> | |||
*[[Carcinosarcoma]].<ref name=pmid18318577/> | |||
Common tumours that uncommonly have the pattern: | |||
*[[Gastric adenocarcinoma]].<ref>URL: [http://cat.inist.fr/?aModele=afficheN&cpsidt=2504165 http://cat.inist.fr/?aModele=afficheN&cpsidt=2504165]. Accessed on: 26 April 2011.</ref> | |||
==Sarcomas cytokeratins== | ==Sarcomas cytokeratins== | ||