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Difference between revisions of "Neurofibroma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Neurofibroma_(3).jpg | |||
| Width = | |||
| Caption = Neurofibroma. [[H&E stain]]. | |||
| Micro = spindle cells with wavy nuclei without pleomorphism ("shredded carrots"), +/-arranged in fascicles and intermixed with collagen, moderately increased of cellularity, poorly ''or'' well-circumscribed, +/-plexiform growth pattern ("bag of worms"), +/-mast cells (useful) | |||
| Subtypes = [[plexiform neurofibroma]] | |||
| LMDDx = [[schwannoma]], [[dermatofibrosarcoma protuberans]], [[ganglioneuroma]], neurotized [[melanocytic nevus]], [[MPNST]] | |||
| Stains = S-100 +ve, CD34 +ve, EMA +ve/-ve, NF +ve/-ve | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = "bag of worms" appearance (plexiform neurofibroma) | |||
| Grossing = | |||
| Site = [[soft tissue lesions|soft tissue]] - [[peripheral nerve sheath tumours]] | |||
| Assdx = | |||
| Syndromes = [[neurofibromatosis type 1]] | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = [[painful skin lesion]] | |||
| Prevalence = not common | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign if isolated | |||
| Other = | |||
| ClinDDx = | |||
}} | |||
'''Neurofibroma''' is an uncommon [[skin]] lesion. This article also includes '''plexiform neurofibroma'''. | '''Neurofibroma''' is an uncommon [[skin]] lesion. This article also includes '''plexiform neurofibroma'''. | ||