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Difference between revisions of "Schwannoma"
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = | | Image = Schwannoma - Antoni A and B - very high mag.jpg | ||
| Width = | | Width = | ||
| Caption = | | Caption = Schwannoma showing Antoni A and Antoni B areas. [[H&E stain]]. | ||
| Micro = Antoni A areas (cellular, fibrillary, polar, elongated), Antoni B area (pauci-cellular, loose microcystic tissue), Verocay bodies (paucinuclear area surrounded by nuclei), hyaline thickened [[blood vessel]]s, thick capsule. | | Micro = Antoni A areas (cellular, fibrillary, polar, elongated), Antoni B area (pauci-cellular, loose microcystic tissue), Verocay bodies (paucinuclear area surrounded by nuclei), hyaline thickened [[blood vessel]]s, thick capsule. | ||
+/-peripheral lymphoid cuff (esp. GI tract) | +/-peripheral lymphoid cuff (esp. GI tract) | ||
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| LMDDx = [[meningioma]], [[leiomyoma]], [[GIST]], [[intranodal palisaded myofibroblastoma]] | | LMDDx = [[meningioma]], [[leiomyoma]], [[GIST]], [[intranodal palisaded myofibroblastoma]] | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = S-100 +ve, EMA -ve, CD34 +ve | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
| Line 60: | Line 60: | ||
*[[Leiomyoma]]. | *[[Leiomyoma]]. | ||
*[[Gastrointestinal stromal tumour]]. | *[[Gastrointestinal stromal tumour]]. | ||
*[[MPNST]] - schwannoma with ancient change has no significant mitotic activity.<ref name=pmid17244372>{{Cite journal | last1 = Chan | first1 = PT. | last2 = Tripathi | first2 = S. | last3 = Low | first3 = SE. | last4 = Robinson | first4 = LQ. | title = Case report--ancient schwannoma of the scrotum. | journal = BMC Urol | volume = 7 | issue = | pages = 1 | month = | year = 2007 | doi = 10.1186/1471-2490-7-1 | PMID = 17244372 }}</ref> | |||
===Images=== | ===Images=== | ||