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Difference between revisions of "Clear cell sarcoma"
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| Molecular = t(12;22) | | Molecular = t(12;22) | ||
| IF = | | IF = | ||
| Gross = | | Gross = deep location, usu. extremity | ||
| Grossing = | | Grossing = | ||
| Site = [[soft tissue lesions|soft tissue]] | | Site = [[soft tissue lesions|soft tissue]] | ||
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| Syndromes = | | Syndromes = | ||
| Clinicalhx = | | Clinicalhx = | ||
| Signs = | | Signs = mass | ||
| Symptoms = | | Symptoms = | ||
| Prevalence = | | Prevalence = uncommon | ||
| Bloodwork = | | Bloodwork = | ||
| Rads = | | Rads = | ||
| Endoscopy = | | Endoscopy = | ||
| Prognosis = | | Prognosis = guarded | ||
| Other = | | Other = | ||
| ClinDDx = | | ClinDDx = | ||
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==General== | ==General== | ||
*Molecular changes and origin distinct from [[malignant melanoma]]. | *Molecular changes and origin distinct from [[malignant melanoma]]. | ||
* | *Rare soft tissue tumour.<ref name=pmid22693489>{{Cite journal | last1 = Hocar | first1 = O. | last2 = Le Cesne | first2 = A. | last3 = Berissi | first3 = S. | last4 = Terrier | first4 = P. | last5 = Bonvalot | first5 = S. | last6 = Vanel | first6 = D. | last7 = Auperin | first7 = A. | last8 = Le Pechoux | first8 = C. | last9 = Bui | first9 = B. | title = Clear cell sarcoma (malignant melanoma) of soft parts: a clinicopathologic study of 52 cases. | journal = Dermatol Res Pract | volume = 2012 | issue = | pages = 984096 | month = | year = 2012 | doi = 10.1155/2012/984096 | PMID = 22693489 }}</ref> | ||
*Guarded prognosis: 5 year and 10 year survival ~ 60% and 40% in one series.<ref name=pmid22693489/> | |||
*First described in 1965.<ref>URL: [http://www.informaworld.com/smpp/723576818-750600/ftinterface~db=all~content=a789166263~fulltext=713240928 http://www.informaworld.com/smpp/723576818-750600/ftinterface~db=all~content=a789166263~fulltext=713240928]. Accessed on: 5 May 2010.</ref> | |||
== | ==Gross== | ||
*Usually - deep soft tissue ''or'' extremities. | *Usually - deep soft tissue ''or'' extremities. | ||
**Classically associated with tendons and aponeuroses.<ref name=pmid17227118>{{Cite journal | last1 = Dim | first1 = DC. | last2 = Cooley | first2 = LD. | last3 = Miranda | first3 = RN. | title = Clear cell sarcoma of tendons and aponeuroses: a review. | journal = Arch Pathol Lab Med | volume = 131 | issue = 1 | pages = 152-6 | month = Jan | year = 2007 | doi = 10.1043/1543-2165(2007)131[152:CCSOTA]2.0.CO;2 | PMID = 17227118 }}</ref> | **Classically associated with tendons and aponeuroses.<ref name=pmid17227118>{{Cite journal | last1 = Dim | first1 = DC. | last2 = Cooley | first2 = LD. | last3 = Miranda | first3 = RN. | title = Clear cell sarcoma of tendons and aponeuroses: a review. | journal = Arch Pathol Lab Med | volume = 131 | issue = 1 | pages = 152-6 | month = Jan | year = 2007 | doi = 10.1043/1543-2165(2007)131[152:CCSOTA]2.0.CO;2 | PMID = 17227118 }}</ref> | ||
==Microscopic== | ==Microscopic== | ||